Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 9/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | USP2 | O75604 | 5/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.55 |
| ▸ | TP53 | P04637 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001834 | 0.88 | KDM4E (0.62) | LMNACYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6001386 | 0.81 | TP53 (0.58) | LMNACYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6001387 | 0.80 | ALDH1A1 (0.51) | LMNACYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6001863 | 0.79 | GBA1 (0.52) | LMNACYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6001170 | 0.77 | LMNA (0.77) | LMNACYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6001192 | 0.77 | MAPT (0.60) | LMNAMAPK1MEN1KMT2ATP53 | |
| SCHEMBL6001690 | 0.76 | ABCG2 (0.59) | LMNAMAPK1MEN1KMT2ATP53 | |
| SCHEMBL30969595 | 0.73 | HPGD (0.57) | LMNACYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL16404315 | 0.71 | MEN1 (0.80) | LMNACYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL30969598 | 0.71 | CSF1R (0.51) | LMNAMAPK1KMT2ACLK4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | REDDY US THERAPEUTICS, INC. | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | HPSE, ENGASE, UGCG | LMNA 706/4885CYP1A2 1500/4885CYP3A4 2894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.