Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2092050 | 0.91 | PIM1 (0.49) | PIM1PIM2KIF11CYP2D6KMT2A | |
| SCHEMBL2096214 | 0.82 | CCR6 (0.43) | PIM1PIM2CYP2D6GRIN2BKMT2A | |
| SCHEMBL168125 | 0.79 | KIF11 (0.47) | KIF11GRIN2BKMT2AMEN1RAB9A | |
| SCHEMBL13790221 | 0.78 | CYP2D6 (0.50) | PIM1PIM2CYP2D6TRPA1KMT2A | |
| SCHEMBL11408146 | 0.77 | MAPT (0.63) | PIM1PIM2BCHEACHEBACE1 | |
| SCHEMBL11409628 | 0.77 | G6PD (0.56) | BCHEACHEBACE1KIF11KMT2A | |
| SCHEMBL4036809 | 0.77 | KIF11 (0.46) | KIF11GRIN2BKMT2AMEN1RAB9A | |
| Fluoride SCHEMBL28371495 | 0.77 | KIF11 (0.46) | KIF11GRIN2BKMT2AMEN1RAB9A | |
| Ammonia Solution, Strong SCHEMBL2163079 | 0.77 | KIF11 (0.46) | KIF11GRIN2BKMT2AMEN1RAB9A | |
| SCHEMBL29087324 | 0.77 | KIF11 (0.46) | KIF11GRIN2BKMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |