Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | ACP1 | P24666 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ACACA | Q13085 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001926 | 0.82 | ACACA (0.60) | KDM4EHPGDLMNAALDH1A1MAPT | |
| SCHEMBL6001875 | 0.82 | MEN1 (0.49) | KDM4EHPGDLMNAALDH1A1MAPT | |
| SCHEMBL6001924 | 0.82 | KDM4E (0.45) | KDM4EHPGDLMNAALDH1A1MAPT | |
| SCHEMBL6001437 | 0.81 | KDM4E (0.71) | KDM4ELMNAALDH1A1MAPTMEN1 | |
| SCHEMBL5801453 | 0.78 | ACP1 (0.64) | MAPTSMN1; SMN2ACP1MEN1KMT2A | |
| SCHEMBL6001934 | 0.77 | KDM4E (0.64) | KDM4EHPGDLMNAALDH1A1MAPT | |
| SCHEMBL6001899 | 0.75 | MAPT (0.55) | KDM4EHPGDLMNAALDH1A1MAPT | |
| SCHEMBL955714 | 0.74 | SMN1; SMN2 (1.00) | KDM4EHPGDLMNAALDH1A1MAPT | |
| SCHEMBL6534368 | 0.74 | ACACA (0.60) | KDM4EHPGDLMNAALDH1A1MAPT | |
| SCHEMBL6001956 | 0.73 | MEN1 (0.43) | KDM4EHPGDLMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | REDDY US THERAPEUTICS, INC. | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | HPSE, ENGASE, UGCG | KDM4E 2893/4885HPGD 189/4885LMNA 706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.