Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13585880 | 0.82 | TLR8 (0.48) | ALDH1A1KDM4EGAAHPGDMAPT | |
| SCHEMBL27871640 | 0.81 | TLR8 (0.52) | ALDH1A1KDM4EGAAHPGDMAPT | |
| SCHEMBL27871518 | 0.81 | TLR8 (0.52) | ALDH1A1KDM4EGAAHPGDMAPT | |
| SCHEMBL1458588 | 0.81 | TLR8 (0.57) | TLR8ATMSMN1; SMN2LMNATSHR | |
| SCHEMBL790531 | 0.81 | MAPT (0.47) | ALDH1A1KDM4EGAAHPGDMAPT | |
| SCHEMBL10768279 | 0.80 | MAPT (0.47) | ALDH1A1KDM4EGAAHPGDMAPT | |
| SCHEMBL29377718 | 0.79 | TLR8 (0.58) | ALDH1A1KDM4EGAAHPGDMAPT | |
| SCHEMBL22498767 | 0.79 | TLR8 (0.58) | ALDH1A1KDM4EGAAHPGDMAPT | |
| SCHEMBL28203089 | 0.79 | TLR8 (0.58) | ALDH1A1KDM4EGAAHPGDMAPT | |
| SCHEMBL7544070 | 0.77 | TLR8 (0.54) | ALDH1A1KDM4EGAAHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | REDDY US THERAPEUTICS, INC. | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | HPSE, ENGASE, UGCG | ALDH1A1 2033/4885KDM4E 2893/4885GAA 178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.