Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 12/20 | 0.58 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29377718 | 1.00 | TLR8 (0.58) | TLR8TLR7LMNATSHRKDM4E | |
| SCHEMBL22498767 | 1.00 | TLR8 (0.58) | TLR8TLR7LMNATSHRKDM4E | |
| SCHEMBL1458588 | 0.98 | TLR8 (0.57) | TLR8TLR7LMNATSHRATM | |
| SCHEMBL28504818 | 0.92 | TLR8 (0.51) | TLR8TLR7LMNATSHRKDM4E | |
| SCHEMBL28510573 | 0.89 | TLR8 (0.54) | TLR8TLR7LMNATSHR | |
| SCHEMBL28508187 | 0.89 | TLR8 (0.48) | TLR8TLR7LMNATSHRKDM4E | |
| SCHEMBL28229720 | 0.87 | KDM4E (0.55) | TLR8TLR7KDM4EALDH1A1GAA | |
| SCHEMBL28503550 | 0.87 | TLR8 (0.54) | TLR8TLR7LMNACYP3A4MAPT | |
| SCHEMBL28906706 | 0.84 | TLR8 (0.54) | TLR8TLR7LMNACYP3A4MAPT | |
| SCHEMBL27871640 | 0.83 | TLR8 (0.52) | TLR8LMNATSHRKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108250142-A | Amine compounds having anti-inflammatory, antifungal, antiparasitic and anticancer activity | 维尔斯达医疗公司 | 2018-07-06 | — | — | CN | claimed |
| CN-108250142-B | Amine compounds having anti-inflammatory, antifungal, antiparasitic and anticancer activity | 维尔斯达医疗公司 | 2021-01-26 | — | — | CN | disclosed |
| CN-108250142-A | Amine compounds having anti-inflammatory, antifungal, antiparasitic and anticancer activity | 维尔斯达医疗公司 | 2018-07-06 | — | — | CN | disclosed |
| CN-104968200-B | Amine compounds having anti-inflammatory, antifungal, antiparasitic and anticancer activity | 维尔斯达医疗公司 | 2018-03-06 | — | — | CN | disclosed |