SCHEMBL6001958

SCHEMBL6001958

O=C(O)c1ccc(-c2ccc(OCCCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F)c(F)c2F)cc1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RARB P10826 7/20 0.41
RARG P13631 6/20 0.41
RARA P10276 5/20 0.41
PLA2G2D Q9UNK4 1/20 0.39
PTPN11 Q06124 2/20 0.39
PPARD Q03181 5/20 0.39
PDE4A P27815 1/20 0.39
PDE4B Q07343 1/20 0.39
PDE4C Q08493 1/20 0.39
PDE4D Q08499 1/20 0.39
EGFR P00533 1/20 0.37
MRGPRX4 Q96LA9 1/20 0.37
SRD5A2 P31213 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6749716 0.99 PLA2G2D (0.41) RARBRARGRARAPLA2G2DPTPN11
SCHEMBL6751407 0.87 PDK2 (0.39) PLA2G2DPPARD
SCHEMBL6751669 0.86 PDK2 (0.39) PLA2G2DPPARD
SCHEMBL4868253 0.86 APP (0.33)
SCHEMBL6749810 0.81 LMNA (0.51) PLA2G2DPPARDMRGPRX4
SCHEMBL7528750 0.80 HDAC1 (0.41) RARBRARAPTPN11
SCHEMBL9406144 0.80 PTPN11 (0.60) RARBPLA2G2DPTPN11
SCHEMBL4862292 0.79 RARB (0.38) RARBPLA2G2DPTPN11
SCHEMBL4862352 0.79 RARB (0.38) RARBPLA2G2DPTPN11
SCHEMBL4872013 0.79 RARB (0.59) RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7083832-B2 Partially fluorinated liquid crystal material DISPLAYTECH, INC. (US) 2006-08-01 US disclosed
US-6703082-B1 VARIOUS NAPHTHALENE-CONTAINING LIQUID CRYSTALS DISPLAYTECH, INC. 2004-03-09 US disclosed
US-20030017278-A1 Partially fluorinated liquid crystal material CITIZEN FINETECH MIYOTA CO., LTD. (JP) 2003-01-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030017278-A1 Partially fluorinated liquid crystal material LEF1, SETDB1, INF2 RARB 3093/4885RARG 2932/4885RARA 2708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.