Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.69 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30458991 | 0.95 | CYP4F2 (0.71) | CYP4F2CYP4A11TDP1FFAR1KCNH2 | |
| SCHEMBL24041871 | 0.95 | CYP4F2 (0.71) | CYP4F2CYP4A11TDP1FFAR1KCNH2 | |
| SCHEMBL9442321 | 0.92 | CYP4F2 (0.61) | CYP4F2CYP4A11TDP1FFAR1PPARG | |
| SCHEMBL23720120 | 0.90 | CYP4F2 (0.59) | CYP4F2CYP4A11FFAR1KCNH2PPARG | |
| SCHEMBL9819766 | 0.89 | CYP4F2 (0.53) | CYP4F2CYP4A11FFAR1PPARGPPARA | |
| SCHEMBL8767703 | 0.89 | CYP4F2 (0.61) | CYP4F2CYP4A11FFAR1KCNH2PPARG | |
| SCHEMBL4165319 | 0.85 | FFAR1 (0.69) | TDP1FFAR1DRD2DRD4DRD3 | |
| SCHEMBL10334435 | 0.84 | CYP4F2 (0.69) | CYP4F2CYP4A11TDP1FFAR1KCNH2 | |
| SCHEMBL8500544 | 0.83 | FFAR1 (0.67) | TDP1FFAR1DRD2DRD4DRD3 | |
| SCHEMBL25175611 | 0.83 | FFAR1 (0.76) | FFAR1PPARGPPARACYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1655280-A1 | Dicarboxylic acid derivates with pharmaceutical properties | Bayer HealthCare AG (DE) | 2006-05-10 | — | — | EP | disclosed |
| US-6864287-B1 | Derivatives of dicarboxylic acid having pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2005-03-08 | — | — | US | disclosed |
| EP-1216222-A2 | NOVEL DERIVATIVES OF DICARBOXYLIC ACID HAVING PHARMACEUTICAL PROPERTIES | Bayer Aktiengesellschaft (DE) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019776-A2 | NOVEL DERIVATIVES OF DICARBOXYLIC ACID HAVING PHARMACEUTICAL PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-03-22 | — | — | WO | disclosed |