Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.59 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.59 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24041871 | 0.92 | CYP4F2 (0.71) | CYP4F2CYP4A11LTA4HEPHX2KCNH2 | |
| SCHEMBL30458991 | 0.92 | CYP4F2 (0.71) | CYP4F2CYP4A11LTA4HEPHX2KCNH2 | |
| SCHEMBL6001982 | 0.90 | CYP4F2 (0.69) | CYP4F2CYP4A11LTA4HEPHX2KCNH2 | |
| SCHEMBL8767703 | 0.89 | CYP4F2 (0.61) | CYP4F2CYP4A11LTA4HEPHX2KCNH2 | |
| SCHEMBL20945397 | 0.89 | CYP4F2 (0.53) | CYP4F2CYP4A11KCNH2PPARGPPARA | |
| SCHEMBL5760533 | 0.87 | CYP4F2 (0.79) | CYP4F2CYP4A11LTA4HEPHX2MAOB | |
| SCHEMBL611426 | 0.86 | CYP4F2 (0.50) | CYP4F2CYP4A11LTA4HKCNH2PPARG | |
| SCHEMBL10235887 | 0.86 | PPARA (0.56) | CYP4F2CYP4A11KCNH2PPARGPPARA | |
| SCHEMBL9819766 | 0.85 | CYP4F2 (0.53) | CYP4F2CYP4A11PPARGPPARAMAOA | |
| SCHEMBL10235872 | 0.84 | PPARA (0.58) | CYP4F2CYP4A11PPARGPPARAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238133-A1 | CYCLOPROPANATION METHOD | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238133-A1 | CYCLOPROPANATION METHOD | ADH1A, ADH1C, ADH5 | CYP4F2 179/4885CYP4A11 38/4885LTA4H 901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.