Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 13/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1748466 | 0.88 | ERN1 (0.44) | ERN1MEN1PLA2G1BPOLBGAA | |
| SCHEMBL30933917 | 0.88 | ERN1 (0.44) | ERN1MEN1PLA2G1BPOLBGAA | |
| SCHEMBL456670 | 0.79 | ERN1 (0.78) | ERN1PIM1 | |
| SCHEMBL30689082 | 0.79 | ERN1 (0.78) | ERN1PIM1 | |
| SCHEMBL1748269 | 0.75 | ERN1 (0.44) | ERN1MAPTKMT2A | |
| SCHEMBL30902339 | 0.75 | ERN1 (0.44) | ERN1MAPTKMT2A | |
| SCHEMBL5318653 | 0.72 | POLB (0.36) | MEN1PLA2G1BPOLBGAAMAPT | |
| SCHEMBL6093685 | 0.70 | ERN1 (1.00) | ERN1PIM1 | |
| SCHEMBL29914868 | 0.68 | ERN1 (0.40) | ERN1MEN1POLBGAAMAPT | |
| SCHEMBL22297792 | 0.68 | ERN1 (0.40) | ERN1MEN1POLBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636221-A2 | NEW AZETIDINE COMPOUNDS | AstraZeneca AB (SE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004110344-A2 | NEW AZETIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2004-12-23 | — | — | WO | disclosed |