SCHEMBL456670

SCHEMBL456670

O=Cc1cc(Cl)cc(O)c1O

nearest known ligand 0.78

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 13/20 0.78
PIM1 P11309 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30689082 1.00 ERN1 (0.78) ERN1PIM1
SCHEMBL6093685 0.88 ERN1 (1.00) ERN1PIM1
SCHEMBL3664243 0.84 ERN1 (0.75) ERN1
SCHEMBL29956081 0.84 ERN1 (0.75) ERN1
SCHEMBL294059 0.82 ERN1 (1.00) ERN1
SCHEMBL29382880 0.82 ERN1 (1.00) ERN1
SCHEMBL15057515 0.82 ERN1 (0.64) ERN1PIM1
SCHEMBL28337241 0.80 ERN1 (0.96) ERN1
SCHEMBL27998889 0.80 ERN1 (0.96) ERN1
SCHEMBL30294924 0.80 ERN1 (0.96) ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117233299-A Method for detecting halogenated polyphenol in drinking water by solid phase extraction-vacuum centrifugal concentration-liquid chromatography tandem mass spectrometry 浙江大学 2023-12-15 CN claimed
CN-104525265-A 2,4-dihydroxy-5-chlorobenzaldehyde amino acid copper complex catalyst, and preparation method and application thereof UNIV LIAOCHENG 2015-04-22 CN claimed
EP-4619097-A1 AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF Samsara Therapeutics Inc. (US) 2025-09-24 EP disclosed
WO-2025106477-A1 NOVEL AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF Samsara Therapeutics Inc. (US) 2025-05-22 WO disclosed
WO-2024107434-A1 AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF Samsara Therapeutics Inc. (US) 2024-05-23 WO disclosed
WO-2024105007-A1 AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF Samsara Therapeutics Inc. (US) 2024-05-23 WO disclosed
CN-117233299-A Method for detecting halogenated polyphenol in drinking water by solid phase extraction-vacuum centrifugal concentration-liquid chromatography tandem mass spectrometry 浙江大学 2023-12-15 CN disclosed
US-11008345-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2021-05-18 US disclosed
US-11008345-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2021-05-18 US disclosed
CN-108727176-B Method for preparing 5-halogen-2, 3-dihydroxy benzaldehyde 荆楚理工学院 2021-05-18 CN disclosed
CN-108610356-B Benzoxaborole derivatives for the treatment of bacterial infections 阿纳科制药公司 2021-02-26 CN disclosed
US-6004808-A STABLE ISOLATED MAMMALIAN CELL FOR SCREENING ASSAYS; WITH HETEROLOGOUS PROMOTERS CONTROLLING GENE EXPRESSION OF G-ALPHA15 PROTEIN, A G-PROTEIN COUPLED RECEPTOR, AND A REPORTER GENE WHOSE EXPRESSION IS MODULATED BY THE G-PROTEIN AURORA BIOSCIENCES CORPORATION (US) 1999-12-21 US disclosed
EP-0834074-B1 DETECTION OF TRANSMEMBRANE POTENTIALS BY OPTICAL METHODS UNIV CALIFORNIA (US) 1999-11-03 EP disclosed
US-5955604-A Substrates for β-lactamase and uses thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1999-09-21 US disclosed
US-5741657-A MEASURING GENE EXPRESSION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-04-21 US disclosed
EP-0834074-A1 DETECTION OF TRANSMEMBRANE POTENTIALS BY OPTICAL METHODS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-04-08 EP disclosed
EP-0817785-A2 SUBSTRATES FOR BETA-LACTAMASE AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-01-14 EP disclosed
WO-1997048820-A1 PROMISCUOUS G-PROTEIN COMPOSITIONS AND THEIR USE AURORA BIOSCIENCES CORPORATION (US) 1997-12-24 WO disclosed
WO-1996041166-A2 DETECTION OF TRANSMEMBRANE POTENTIALS BY OPTICAL METHODS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1996-12-19 WO disclosed
WO-1996030540-A2 SUBSTRATES FOR BETA-LACTAMASE AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1996-10-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11008345-B2 Boron-containing small molecules BCL6B, BTD, BROX ERN1 3162/4885PIM1 1294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.