Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTH | P32929 | 13/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12190592 | 0.81 | RRM2 (0.48) | LMNAHKDC1GAA | |
| SCHEMBL14938442 | 0.77 | SMN1; SMN2 (0.46) | MEN1KMT2ALMNAALDH1A1HKDC1 | |
| SCHEMBL1982234 | 0.75 | CTH (1.00) | CTHMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL1982233 | 0.75 | CTH (1.00) | CTHMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL6002503 | 0.75 | SMN1; SMN2 (0.45) | MEN1KMT2ALMNAALDH1A1HKDC1 | |
| SCHEMBL9131054 | 0.73 | RAB9A (0.59) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL10875086 | 0.71 | SMN1; SMN2 (0.46) | CTHMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL15882846 | 0.70 | MEN1 (0.55) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL14938600 | 0.70 | SMN1; SMN2 (0.43) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL8344559 | 0.70 | HRH3 (0.44) | LMNAALDH1A1MAPTTAAR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1734939-A1 | ANTI-PARASITIC COMPOUNDS AND METHODS OF THEIR USE | The Regents of The University of California (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005087211-A1 | ANTI-PARASITIC COMPOUNDS AND METHODS OF THEIR USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-09-22 | — | — | WO | disclosed |