Diphenylether

Diphenylether

SCHEMBL6002228

C=CC(=O)OCC(C)O.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.54
TSHR P16473 1/20 0.51
LMNA P02545 3/20 0.50
TGM2 P21980 1/20 0.45
ALDH1A1 P00352 3/20 0.45
NPY5R Q15761 1/20 0.42
PTGS1 P23219 1/20 0.42
HTR1D P28221 1/20 0.42
HTR1B P28222 1/20 0.42
KDM4E B2RXH2 2/20 0.41
MAPT P10636 1/20 0.41
RAB9A P51151 3/20 0.40
GAA P10253 2/20 0.40
GLA P06280 1/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
NPC1 O15118 1/20 0.40
HPGD P15428 1/20 0.40
CRHBP P24387 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28092989 0.87 TSHR (0.67) THRBTSHRLMNAALDH1A1MAPT
Styrene SCHEMBL25312124 0.86 TSHR (0.53) THRBTSHRLMNAALDH1A1KDM4E
Styrene SCHEMBL2539780 0.83 TSHR (0.50) THRBTSHRLMNAALDH1A1KDM4E
Diphenylether SCHEMBL23165006 0.82 THRB (0.58) THRBTSHRLMNATGM2ALDH1A1
Diphenylether SCHEMBL8825712 0.82 LMNA (0.55) LMNAALDH1A1NPY5RPTGS1HTR1D
SCHEMBL181493 0.81 TSHR (0.56) THRBTSHRLMNAALDH1A1MAPT
SCHEMBL299561 0.81 THRB (0.58) THRBTSHRLMNAALDH1A1HTT
SCHEMBL33585 0.81
SCHEMBL27800525 0.81
SCHEMBL27821519 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7135229-B2 Urethane (meth)acrylate oligomer with an alkyd backbone derived from renewable raw materials such as vegetable oil; solvent-free coating composition for optical fiber containing a photoinitiator and a reactive diluent; more environmentally friendly than than ordinary polyesters DSM IP ASSETS B.V. (NL) 2006-11-14 US disclosed
EP-1232196-B1 RADIATION-CURABLE COATING COMPOSITION DSM IP ASSETS BV (NL) 2005-09-14 EP disclosed
US-20040048946-A1 Radiation-curable coating composition DSM IP ASSETS B.V. (NL) 2004-03-11 US disclosed
US-6638616-B2 Optical fiber having a radiation- curable urethane (meth)acrylate oligomer consists of an alkyd backbone, a reactive diluent, and a photoinitiators DSM N.V. (NL) 2003-10-28 US disclosed
US-20020151615-A1 RADIATION-CURABLE COATING COMPOSITION DSM IP ASSETS B.V. (NL) 2002-10-17 US disclosed
EP-1232196-A1 RADIATION-CURABLE COATING COMPOSITION DSM N.V. (NL) 2002-08-21 EP disclosed
WO-2001027181-A1 RADIATION-CURABLE COATING COMPOSITION DSM N.V. (NL) 2001-04-19 WO disclosed