Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ICMT | O60725 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002360 | 1.00 | KMT2A (0.47) | KMT2ATDP1L3MBTL1TSHRALDH1A1 | |
| SCHEMBL6002692 | 1.00 | KMT2A (0.47) | KMT2ATDP1L3MBTL1TSHRALDH1A1 | |
| SCHEMBL6002764 | 1.00 | KMT2A (0.47) | KMT2ATDP1L3MBTL1TSHRALDH1A1 | |
| SCHEMBL6003625 | 0.94 | L3MBTL1 (0.49) | KMT2ATDP1L3MBTL1TSHRALDH1A1 | |
| SCHEMBL6002262 | 0.87 | TSHR (0.44) | KMT2ATDP1TSHRALDH1A1LMNA | |
| SCHEMBL6002357 | 0.87 | TSHR (0.44) | KMT2ATDP1TSHRALDH1A1LMNA | |
| SCHEMBL6002761 | 0.87 | TSHR (0.44) | KMT2ATDP1TSHRALDH1A1LMNA | |
| SCHEMBL6002685 | 0.87 | TSHR (0.44) | KMT2ATDP1TSHRALDH1A1LMNA | |
| SCHEMBL6002725 | 0.86 | TSHR (0.49) | KMT2ATSHRALDH1A1LMNANPC1 | |
| SCHEMBL27729849 | 0.86 | TSHR (0.49) | KMT2ATSHRALDH1A1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |