Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002764 | 0.94 | KMT2A (0.47) | L3MBTL1TDP1KMT2AALDH1A1TSHR | |
| SCHEMBL6002692 | 0.94 | KMT2A (0.47) | L3MBTL1TDP1KMT2AALDH1A1TSHR | |
| SCHEMBL6002360 | 0.94 | KMT2A (0.47) | L3MBTL1TDP1KMT2AALDH1A1TSHR | |
| SCHEMBL6002265 | 0.94 | KMT2A (0.47) | L3MBTL1TDP1KMT2AALDH1A1TSHR | |
| SCHEMBL6003620 | 0.86 | TSHR (0.41) | L3MBTL1TDP1KMT2AALDH1A1TSHR | |
| SCHEMBL6002982 | 0.85 | TSHR (0.46) | L3MBTL1TDP1KMT2AALDH1A1TSHR | |
| SCHEMBL6002978 | 0.84 | TSHR (0.45) | L3MBTL1TDP1KMT2AALDH1A1TSHR | |
| SCHEMBL8395346 | 0.83 | CYP3A4 (0.44) | L3MBTL1TDP1KMT2AALDH1A1TSHR | |
| SCHEMBL8395345 | 0.83 | TSHR (0.44) | L3MBTL1TDP1KMT2AALDH1A1TSHR | |
| SCHEMBL6001172 | 0.81 | TSHR (0.47) | L3MBTL1TDP1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |