Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750832 | 0.81 | MAPT (0.50) | MAPTHTTNPC1RAB9AHPGD | |
| SCHEMBL245209 | 0.81 | MAPT (0.50) | MAPTHTTNPC1RAB9AHPGD | |
| SCHEMBL30461968 | 0.81 | MAPT (0.50) | MAPTHTTNPC1RAB9AHPGD | |
| SCHEMBL26385190 | 0.77 | NPC1 (0.48) | MAPTHTTNPC1RAB9AHPGD | |
| SCHEMBL21675477 | 0.77 | MAPT (0.46) | MAPTHTTNPC1RAB9AHPGD | |
| SCHEMBL22643737 | 0.77 | MAPT (0.46) | MAPTHTTNPC1RAB9AHPGD | |
| SCHEMBL18904614 | 0.77 | MAPT (0.46) | MAPTHTTNPC1RAB9AHPGD | |
| SCHEMBL2230553 | 0.77 | NPC1 (0.48) | MAPTHTTNPC1RAB9AHPGD | |
| SCHEMBL17716129 | 0.76 | MAPT (0.45) | MAPTHTTNPC1RAB9AHPGD | |
| SCHEMBL19399594 | 0.76 | MAPT (0.45) | MAPTHTTNPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0813424-B2 | ORAL PHARMACEUTICAL DOSAGE FORMS COMPRISING A PROTON PUMP INHIBITOR AND AN ANTACID AGENT OR ALGINATE | ASTRAZENECA AB (SE) | 2009-08-05 | — | — | EP | disclosed |
| US-20060199917-A1 | thermoplastic elastomer exhibiting high recyclability and oil resistance as well as excellent mechanical strength, and in particular, excellent resistance to compression set is provided. The thermoplastic resin with epoxy, hydroxy or nitrogen groups in backbone | YOKOHAMA RUBBER CO., LTD., THE (JP) | 2006-09-07 | — | — | US | disclosed |