SCHEMBL4750832

SCHEMBL4750832

Cc1ccccc1NC(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.50
HTT P42858 1/20 0.50
TDP1 Q9NUW8 3/20 0.48
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
IDO1 P14902 1/20 0.45
ALDH1A1 P00352 5/20 0.45
HPGD P15428 3/20 0.45
GAA P10253 2/20 0.43
KDM4E B2RXH2 1/20 0.43
TSHR P16473 2/20 0.43
ACHE P22303 1/20 0.43
LMNA P02545 1/20 0.41
CYP3A4 P08684 1/20 0.41
THRB P10828 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
RECQL P46063 1/20 0.41
ATM Q13315 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30461968 1.00 MAPT (0.50) MAPTHTTTDP1NPC1RAB9A
SCHEMBL21675477 0.86 MAPT (0.46) MAPTHTTTDP1NPC1RAB9A
SCHEMBL245209 0.85 MAPT (0.50) MAPTHTTTDP1NPC1RAB9A
SCHEMBL2962223 0.84 TDP1 (0.57) MAPTHTTTDP1IDO1ALDH1A1
SCHEMBL4797007 0.82 IDO1 (0.44) MAPTHTTTDP1NPC1RAB9A
Propionamide SCHEMBL28511810 0.82 PGR (0.47) MAPTTDP1NPC1RAB9AALDH1A1
SCHEMBL18904614 0.81 MAPT (0.46) MAPTHTTTDP1NPC1RAB9A
SCHEMBL22643737 0.81 MAPT (0.46) MAPTHTTTDP1NPC1RAB9A
SCHEMBL10393919 0.81 KEAP1 (0.48) MAPTHTTTDP1NPC1RAB9A
SCHEMBL26385190 0.81 NPC1 (0.48) MAPTHTTTDP1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3652250-A1 RESIN COMPOSITION Hexcel Composites Limited (GB) 2020-05-20 EP claimed
EP-3652244-A1 RESIN COMPOSITION Hexcel Composites Limited (GB) 2020-05-20 EP claimed
CN-110914355-A Resin composition 赫克塞尔合成有限公司 2020-03-24 CN claimed
CN-110914363-A Resin composition 赫克塞尔合成有限公司 2020-03-24 CN claimed
CN-110156629-A The synthetic method of procarbazine 广州药本君安医药科技股份有限公司 2019-08-23 CN claimed
WO-2019011984-A1 RESIN COMPOSITION HEXCEL COMPOSITES LIMITED (GB) 2019-01-17 WO claimed
WO-2019011982-A1 RESIN COMPOSITION HEXCEL COMPOSITES LIMITED (GB) 2019-01-17 WO claimed
WO-2014071194-A2 METHODS FOR TREATING FIBROMYALGIA KATZ ROBERT S (US) 2014-05-08 WO claimed
WO-2007016190-A2 ANTIPARKINSONIAN ACTION OF PHENYLISOPROPYLAMINES DUKE UNIVERSITY (US) 2007-02-08 WO claimed
US-20070027208-A1 Antiparkinsonian Action of Phenylisopropylamines NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-02-01 US claimed
EP-0469889-B1 (p-Carbonylaminophenyl)-sulphonyl-nitromethane derivatives ZENECA LTD (GB) 1996-01-17 EP claimed
US-5189031-A Inhibitor of enzyme aldose reductase, useful in the treatment of certain peripheral effects of diabetes and galactosemia IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-02-23 US claimed
EP-0469889-A1 (p-Carbonylaminophenyl)-sulphonyl-nitromethane derivatives ZENECA LIMITED (GB) 1992-02-05 EP claimed
EP-0016581-B1 ZIEGLER TYPE CATALYST COMPOSITION EXXON RESEARCH AND ENGINEERING COMPANY (US) 1984-08-08 EP claimed
US-20260015455-A1 EPOXY RESIN COMPOSITION FOR RESIN TRANSFER MOLDING, CURED RESIN PRODUCT, FIBER-REINFORCED COMPOSITE MATERIAL, AND METHOD FOR MANUFACTURING SAME TORAY INDUSTRIES, INC. (JP) 2026-01-15 US disclosed
CN-119390582-A Method for continuously producing N-alkylaniline compounds from nitrobenzene compounds and ketones 浙江工业大学 2025-02-07 CN disclosed
US-20240117130-A1 EPOXY RESIN COMPOSITION FOR FIBER-REINFORCED COMPOSITE MATERIAL, FIBER-REINFORCED COMPOSITE MATERIAL, AND METHOD FOR PRODUCING FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2024-04-11 US disclosed
EP-0016581-B1 ZIEGLER TYPE CATALYST COMPOSITION EXXON RESEARCH AND ENGINEERING COMPANY (US) 1984-08-08 EP disclosed
EP-0016581-A1 Ziegler type catalyst composition EXXON RESEARCH AND ENGINEERING COMPANY (US) 1980-10-01 EP disclosed
US-4224182-A POLYMERIZATION CATALYSTS EXXON RESEARCH & ENGINEERING CO. (US) 1980-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070027208-A1 Antiparkinsonian Action of Phenylisopropylamines PNMT, SNCA, COMT MAPT 393/4885HTT 7/4885TDP1 716/4885
US-20260015455-A1 EPOXY RESIN COMPOSITION FOR RESIN TRANSFER MOLDING, CURED RESIN PRODUCT, FIBER-REINFORCED COMPOSITE MATERIAL, AND METHOD FOR MANUFACTURING SAME RFT1, RER1, TERB1 MAPT 1778/4885HTT 2899/4885TDP1 2639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.