Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750832 | 1.00 | MAPT (0.50) | MAPTHTTTDP1NPC1RAB9A | |
| SCHEMBL21675477 | 0.86 | MAPT (0.46) | MAPTHTTTDP1NPC1RAB9A | |
| SCHEMBL245209 | 0.85 | MAPT (0.50) | MAPTHTTTDP1NPC1RAB9A | |
| SCHEMBL2962223 | 0.84 | TDP1 (0.57) | MAPTHTTTDP1IDO1ALDH1A1 | |
| SCHEMBL4797007 | 0.82 | IDO1 (0.44) | MAPTHTTTDP1NPC1RAB9A | |
| Propionamide SCHEMBL28511810 | 0.82 | PGR (0.47) | MAPTTDP1NPC1RAB9AALDH1A1 | |
| SCHEMBL18904614 | 0.81 | MAPT (0.46) | MAPTHTTTDP1NPC1RAB9A | |
| SCHEMBL22643737 | 0.81 | MAPT (0.46) | MAPTHTTTDP1NPC1RAB9A | |
| SCHEMBL10393919 | 0.81 | KEAP1 (0.48) | MAPTHTTTDP1NPC1RAB9A | |
| SCHEMBL26385190 | 0.81 | NPC1 (0.48) | MAPTHTTTDP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120463608-A | Preparation method of high-purity prilocaine impurity G | 山东明仁福瑞达制药股份有限公司 | 2025-08-12 | — | — | CN | disclosed |
| CN-116496220-A | Preparation method of prilocaine impurity IV | 斯坦德药典标准物质研发(湖北)有限公司 | 2023-07-28 | — | — | CN | disclosed |