Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | RXRB | P28702 | 2/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7619419 | 0.92 | NPSR1 (0.43) | NPSR1RAB9AMAPTLMNAL3MBTL1 | |
| SCHEMBL13443487 | 0.90 | PPARG (0.40) | RAB9AMAPTLMNAL3MBTL1PTGER1 | |
| SCHEMBL6002321 | 0.85 | RXRA (0.51) | NPSR1RAB9AL3MBTL1RXRARXRB | |
| SCHEMBL3602387 | 0.85 | MAPT (0.37) | RAB9AMAPTLMNAL3MBTL1PTGER1 | |
| SCHEMBL13443503 | 0.83 | PPARD (0.44) | RAB9AMAPTLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL6001865 | 0.83 | PPARG (0.43) | RAB9AMAPTL3MBTL1PTGER1PTGER4 | |
| SCHEMBL6001819 | 0.82 | PPARG (0.42) | NPSR1RAB9AMAPTL3MBTL1RXRA | |
| SCHEMBL3589134 | 0.82 | PPARG (0.35) | NPSR1RAB9AMAPTLMNAL3MBTL1 | |
| SCHEMBL13009644 | 0.80 | NPSR1 (0.46) | NPSR1RAB9AMAPTLMNAL3MBTL1 | |
| SCHEMBL3591129 | 0.79 | MAPT (0.39) | RAB9AMAPTL3MBTL1KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1655280-A1 | Dicarboxylic acid derivates with pharmaceutical properties | Bayer HealthCare AG (DE) | 2006-05-10 | — | — | EP | disclosed |
| US-6864287-B1 | Derivatives of dicarboxylic acid having pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2005-03-08 | — | — | US | disclosed |