Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | PTGFR | P43088 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002376 | 0.82 | NPSR1 (0.44) | NPSR1RAB9AL3MBTL1PTGER1PTGER4 | |
| SCHEMBL13443165 | 0.82 | PTGFR (0.40) | PPARGPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL6000368 | 0.78 | PPARG (0.54) | PPARGPTGFRPPARAADRB2 | |
| SCHEMBL3600337 | 0.78 | PPARG (0.43) | PPARGL3MBTL1PTGFRPPARAADRB2 | |
| SCHEMBL13009644 | 0.76 | NPSR1 (0.46) | NPSR1RAB9AL3MBTL1PTGER1PTGER4 | |
| SCHEMBL7990040 | 0.75 | PTGER1 (0.60) | PTGER1PTGER4PTGER3PTGER2ABCB1 | |
| SCHEMBL10986377 | 0.75 | TRPA1 (0.50) | PPARGL3MBTL1PTGER1PTGER2PTGFR | |
| SCHEMBL13061697 | 0.74 | NPSR1 (0.43) | NPSR1RAB9AL3MBTL1PTGER1PTGER4 | |
| SCHEMBL6002321 | 0.73 | RXRA (0.51) | NPSR1RAB9AL3MBTL1PTGER1PTGER4 | |
| SCHEMBL3930253 | 0.73 | HTR1A (0.59) | L3MBTL1PTGER1PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1655280-A1 | Dicarboxylic acid derivates with pharmaceutical properties | Bayer HealthCare AG (DE) | 2006-05-10 | — | — | EP | disclosed |