Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | XBP1 | P17861 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090981 | 0.85 | KMT2A (0.66) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2056317 | 0.84 | EPHX2 (0.67) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2090978 | 0.82 | EPHX2 (0.63) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9842921 | 0.82 | EPHX2 (0.63) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL19785093 | 0.81 | ALDH1A1 (0.72) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL19721129 | 0.81 | POLB (0.75) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2535860 | 0.80 | EPHX2 (0.65) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL19721197 | 0.80 | ALDH1A1 (0.70) | ALDH1A1KMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL2092931 | 0.80 | EPHX2 (0.69) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2092934 | 0.80 | EPHX2 (0.69) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |