Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 4/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.63 |
| ▸ | KLK7 | P49862 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19721129 | 0.87 | POLB (0.75) | ALDH1A1SMN1; SMN2MAPTMAPK1KDM4E | |
| SCHEMBL2098410 | 0.84 | MTNR1A (0.70) | ALDH1A1SMN1; SMN2MAPTMAPK1KDM4E | |
| SCHEMBL2954416 | 0.82 | L3MBTL1 (0.71) | ALDH1A1SMN1; SMN2MAPTMAPK1KDM4E | |
| SCHEMBL9313874 | 0.82 | L3MBTL1 (0.76) | ALDH1A1SMN1; SMN2MAPTMAPK1KDM4E | |
| SCHEMBL6002399 | 0.81 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL19721130 | 0.81 | HPGD (1.00) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL27670724 | 0.81 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MAPTMAPK1KDM4E | |
| SCHEMBL11727915 | 0.81 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2MAPTHPGDRAB9A | |
| SCHEMBL19721197 | 0.81 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2MAPTHPGDRAB9A | |
| SCHEMBL2098408 | 0.81 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2MAPTMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10350192-B2 | Lactate dehydrogenase inhibitor and antiepileptic drug containing the same | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2019-07-16 | — | — | US | disclosed |
| US-20180015068-A1 | LACTATE DEHYDROGENASE INHIBITOR AND ANTIEPILEPTIC DRUG CONTAINING THE SAME | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2018-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180015068-A1 | LACTATE DEHYDROGENASE INHIBITOR AND ANTIEPILEPTIC DRUG CONTAINING THE SAME | LDHA, LDHB, ALDH5A1 | ALDH1A1 38/4885SMN1; SMN2 2719/4885MAPT 569/4885 |
| US-10350192-B2 | Lactate dehydrogenase inhibitor and antiepileptic drug containing the same | LDHA, LDHB, ALDH5A1 | ALDH1A1 38/4885SMN1; SMN2 2719/4885MAPT 569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.