Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | RRM2 | P31350 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17666943 | 0.84 | ALDH1A1 (0.53) | MAOAKDM4EGAAL3MBTL1POLB | |
| SCHEMBL17666941 | 0.84 | ALDH1A1 (0.53) | MAOAKDM4EGAAL3MBTL1POLB | |
| SCHEMBL6746611 | 0.84 | ABAT (0.38) | MAOAKDM4EL3MBTL1LMNAALDH1A1 | |
| SCHEMBL6002142 | 0.82 | HTT (0.49) | MAOAKDM4EGAAL3MBTL1POLB | |
| SCHEMBL6002151 | 0.81 | MAOA (0.46) | MAOAKDM4ERRM2POLBLMNA | |
| SCHEMBL6002241 | 0.81 | POLB (0.47) | MAOAKDM4EGAAL3MBTL1POLB | |
| SCHEMBL28188941 | 0.80 | MAOA (0.52) | MAOAALDH1A1 | |
| SCHEMBL6002032 | 0.79 | MAOA (0.44) | MAOAGAAPOLBALDH1A1 | |
| SCHEMBL6000574 | 0.74 | POLB (0.47) | MAOAKDM4EGAAL3MBTL1POLB | |
| SCHEMBL20831615 | 0.74 | ESR1 (0.39) | KDM4EL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1734939-A1 | ANTI-PARASITIC COMPOUNDS AND METHODS OF THEIR USE | The Regents of The University of California (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005087211-A1 | ANTI-PARASITIC COMPOUNDS AND METHODS OF THEIR USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-09-22 | — | — | WO | disclosed |