Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.49 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6003637 | 0.96 | CYP2D6 (0.53) | KDM4EALDH1A1HPGDL3MBTL1CYP2D6 | |
| SCHEMBL14267492 | 0.76 | RARB (0.71) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9154663 | 0.76 | RARB (0.71) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9154372 | 0.76 | RARB (0.71) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL7775244 | 0.76 | RARB (0.71) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL2204178 | 0.76 | RARB (0.71) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9150185 | 0.76 | RARB (0.71) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9153965 | 0.76 | RARB (0.71) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9155028 | 0.76 | RARB (0.71) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9150611 | 0.76 | RARB (0.71) | KDM4EALDH1A1HPGDL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |