Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | OXTR | P30559 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29713511 | 0.82 | NR1H2 (0.39) | NR1H2CTSLCTSSKDM1AOXTR | |
| SCHEMBL15649736 | 0.82 | NR1H2 (0.39) | NR1H2CTSLCTSSKDM1AOXTR | |
| SCHEMBL20955744 | 0.78 | NOTUM (0.57) | KDM1ANOTUMOXTRAVPR1A | |
| SCHEMBL1997435 | 0.74 | PROKR1 (0.40) | — | |
| SCHEMBL2123391 | 0.74 | PIK3CA (0.41) | NR1H2CTSLCTSSPIK3CA | |
| SCHEMBL6002974 | 0.73 | CYP11B2 (0.38) | NR1H2KDM1ANOTUM | |
| SCHEMBL5599315 | 0.73 | DPP4 (0.37) | KDM1ANOTUM | |
| SCHEMBL1195029 | 0.73 | AKT1 (0.41) | KDM1ANOTUM | |
| Hydrochloric Acid SCHEMBL17008459 | 0.72 | AKT1 (0.41) | KDM1ANOTUM | |
| SCHEMBL1222469 | 0.72 | NOTUM (0.53) | KDM1ANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694677-A1 | SPIROPIPERIDINE DERIVATIVES FOR CONTROLLING PESTS | Syngenta Participations AG (CH) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005061500-A1 | SPIROPIPERIDINE DERIVATIVES FOR CONTROLLING PESTS | SYNGENTA PARTICIPATIONS AG (CH) | 2005-07-07 | — | — | WO | disclosed |