Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | ADK | P55263 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19782078 | 0.87 | NISCH (0.44) | NISCHMTORADKALDH1A1MEN1 | |
| SCHEMBL28829249 | 0.87 | NISCH (0.43) | NISCHMTORADKALDH1A1MEN1 | |
| SCHEMBL22096835 | 0.83 | TAAR1 (0.49) | NISCHMTORADKALDH1A1MEN1 | |
| SCHEMBL21883582 | 0.83 | NISCH (0.40) | NISCHMTORADKALDH1A1MEN1 | |
| SCHEMBL19769010 | 0.83 | TAAR1 (0.48) | NISCHMTORADKALDH1A1MEN1 | |
| SCHEMBL1436578 | 0.79 | CSNK1A1 (0.46) | NISCHMTORADKALDH1A1MEN1 | |
| SCHEMBL1289114 | 0.78 | NISCH (0.53) | NISCHMTORADKALDH1A1MEN1 | |
| SCHEMBL29985833 | 0.78 | NISCH (0.53) | NISCHMTORADKALDH1A1MEN1 | |
| SCHEMBL24088205 | 0.77 | HTR1A (0.48) | NISCHMTORADKMEN1KMT2A | |
| SCHEMBL28382846 | 0.77 | CSNK1A1 (0.56) | NISCHMTORADKALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102146077-A | Fluoreneimidazole derivatives and preparation method thereof | UNIV SHANGHAI | 2011-08-10 | — | — | CN | disclosed |
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |