SCHEMBL24088205

SCHEMBL24088205

Fc1cccc(OCc2ccccc2)c1-c1ncc[nH]1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 1/20 0.48
SLC6A2 P23975 1/20 0.48
SLC6A4 P31645 1/20 0.48
SLC6A3 Q01959 1/20 0.48
KDM1A O60341 2/20 0.47
MRGPRX4 Q96LA9 2/20 0.43
MAPT P10636 1/20 0.43
MAPK1 P28482 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
LTA4H P09960 2/20 0.42
MAPK14 Q16539 1/20 0.42
NPC1 O15118 2/20 0.42
ADRA1A P35348 1/20 0.41
MTOR P42345 1/20 0.41
ADK P55263 1/20 0.41
NISCH Q9Y2I1 1/20 0.41
DHODH Q02127 1/20 0.40
IDO1 P14902 1/20 0.40
SYK P43405 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24088196 0.81 APP (0.46) HTR1ASLC6A2SLC6A4SLC6A3MRGPRX4
SCHEMBL6002691 0.77 NISCH (0.50) MAPK14ADRA1AMTORADKNISCH
SCHEMBL8541063 0.76 LTA4H (0.53) HTR1AMRGPRX4MAPTMAPK1TDP1
SCHEMBL4267531 0.72 MRGPRX4 (0.63) HTR1ASLC6A2SLC6A4SLC6A3KDM1A
SCHEMBL8216313 0.72 MAPT (0.69) HTR1ASLC6A2SLC6A4SLC6A3KDM1A
SCHEMBL7328641 0.71 IKBKB (0.49) MRGPRX4MAPTL3MBTL1LTA4HMAPK14
SCHEMBL31195406 0.71 KDM1A (0.48) HTR1ASLC6A2SLC6A4SLC6A3KDM1A
SCHEMBL30080427 0.71 MAPT (0.58) HTR1ASLC6A2SLC6A4SLC6A3KDM1A
SCHEMBL9706382 0.71 MAPT (0.58) HTR1ASLC6A2SLC6A4SLC6A3KDM1A
SCHEMBL19782078 0.70 NISCH (0.44) MTORADKNISCHMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118580280-A Organic electroluminescent material and device 环球展览公司 2024-09-03 CN disclosed
CN-118580281-A Organic electroluminescent material and device 环球展览公司 2024-09-03 CN disclosed
CN-113666968-B Organic electroluminescent material and device 环球展览公司 2024-06-28 CN disclosed
US-20210380617-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210380617-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, CRKL, ROS1 HTR1A 4314/4885SLC6A2 4093/4885SLC6A4 4066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.