SCHEMBL600271

SCHEMBL600271

O=C1OC(=O)c2cc(O)cc3cccc1c23

nearest known ligand 0.64

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TYMS P04818 15/20 0.64
BRD1 O95696 1/20 0.43
TAF1 P21675 1/20 0.43
BRPF1 P55201 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29434909 1.00 TYMS (0.64) TYMSBRD1TAF1BRPF1
SCHEMBL9413382 0.86 TYMS (0.46) TYMS
SCHEMBL8323171 0.80 TDP2 (0.55) TYMS
1,8-Naphthalic Anhydride SCHEMBL30415 0.80 TYMS (1.00) TYMS
1,8-Naphthalic Anhydride SCHEMBL29351054 0.80 TYMS (1.00) TYMS
SCHEMBL4957627 0.79 TYMS (0.67) TYMS
SCHEMBL4960941 0.78 TYMS (0.64) TYMS
SCHEMBL22580797 0.78 TYMS (0.64) TYMS
SCHEMBL1565203 0.78 TYMS (0.64) TYMSBRD1TAF1BRPF1
SCHEMBL29713398 0.78 TYMS (0.64) TYMSBRD1TAF1BRPF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111646943-A Binaphthol diimide derivative and preparation method thereof 福州大学 2020-09-11 CN claimed
US-12486362-B2 Polyester polyol comprising an imide moiety and methods of manufacture thereof HUNTSMAN INTERNATIONAL LLC 2025-12-02 US disclosed
EP-3813834-B1 NEW CRBN MODULATORS DANA FARBER CANCER INST INC (US) 2025-03-26 EP disclosed
US-12252578-B2 Polyurethane foam composition comprising an aromatic polyester polyol compound and products made therefrom HUNTSMAN INTERNATIONAL LLC 2025-03-18 US disclosed
US-12030892-B2 CRBN modulators DANA-FARBER CANCER INSTITUTE, INC. (US) 2024-07-09 US disclosed
EP-3825385-B1 DIAGNOSTIC DETERMINATION OF CLEANING PERFORMANCE BY USING FLUORESCENT POLYMERS IN MARKING COMPOSITIONS ECOLAB USA INC (US) 2024-06-12 EP disclosed
US-11999723-B2 Pyrazole-containing macrophage migration inhibitory factor inhibitors YALE UNIVERSITY (US) 2024-06-04 US disclosed
WO-2024100964-A1 ORGANOMETALLIC COMPOUND, SULFONIUM SALT-TYPE COMPOUND, NONION OXIME-TYPE COMPOUND, PHOTOSENSITIVE MATERIAL, ACID GENERATOR, AND PHOTORESIST サンアプロ株式会社 2024-05-16 WO disclosed
US-20230057076-A1 Pyrazole-Containing Macrophage Migration Inhibitory Factor Inhibitors UNIV YALE (US) 2023-02-23 US disclosed
US-20230057076-A1 Pyrazole-Containing Macrophage Migration Inhibitory Factor Inhibitors UNIV YALE (US) 2023-02-23 US disclosed
WO-1987004153-A1 2,3-DIHYDRO-1H-PHENALENE-2-AMINO COMPOUNDS AS ANTI-PSYCHOTIC DRUGS THE UPJOHN COMPANY (US) 1987-07-16 WO disclosed
US-4618555-A PHOTOSENSITIVITY; DURABILITY MITSUBISHI CHEMICAL IND., LTD. (JP) 1986-10-21 US disclosed
EP-0063387-B1 ELECTROPHOTOGRAPHIC PLATE MITSUBISHI KASEI CORPORATION (JP) 1986-07-23 EP disclosed
US-4578469-A COUMARIN DYES HOECHST AKTIENGESELLSCHAFT (DE) 1986-03-25 US disclosed
EP-0150707-A1 Electrophotographic photoreceptor MITSUBISHI KASEI CORPORATION (JP) 1985-08-07 EP disclosed
US-4396696-A Electrophotographic plate having azo compound photosensitive layer MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1983-08-02 US disclosed
EP-0063387-A1 Electrophotographic plate MITSUBISHI KASEI CORPORATION (JP) 1982-10-27 EP disclosed
US-4207107-A Novel ortho-quinone diazide photoresist sensitizers RCA CORPORATION (US) 1980-06-10 US disclosed
US-4204063-A ANTITUMOR AGENTS LABORATORIOS MADE, S.A. (ES) 1980-05-20 US disclosed
US-4002630-A INTERMEDIATES FOR AZO-METHINE DYES HOECHST AKTIENGESELLSCHAFT (DT) 1977-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11999723-B2 Pyrazole-containing macrophage migration inhibitory factor inhibitors MIF, MMP12, CSF1R TYMS 3006/4885BRD1 1832/4885TAF1 4581/4885
US-12030892-B2 CRBN modulators CRBN, CRKL, CDR2 TYMS 4129/4885BRD1 480/4885TAF1 2789/4885
US-20230057076-A1 Pyrazole-Containing Macrophage Migration Inhibitory Factor Inhibitors MIF, MMP12, CSF1R TYMS 3006/4885BRD1 1832/4885TAF1 4581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.