Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.30 |
| ▸ | HTR2B | P41595 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2089333 | 0.77 | DDB1 (0.45) | MAPTALDH1A1HRH3 | |
| SCHEMBL2090778 | 0.71 | SLC6A2 (0.30) | — | |
| SCHEMBL8533774 | 0.69 | MAPT (0.42) | ACHEMAPTHTR2CHTR2B | |
| SCHEMBL8171032 | 0.67 | EGFR (0.49) | MAOBKDM4EACHEALDH1A1HRH3 | |
| SCHEMBL8256707 | 0.67 | PARP10 (0.53) | MAOBKDM4EACHEALDH1A1HRH3 | |
| SCHEMBL18210781 | 0.66 | EGFR (0.48) | MAOBKDM4EACHEALDH1A1HRH3 | |
| SCHEMBL257928 | 0.66 | EGFR (0.48) | MAOBKDM4EACHEALDH1A1HRH3 | |
| SCHEMBL3158901 | 0.66 | CHRNB2 (0.55) | HTR2CHTR2B | |
| SCHEMBL2095318 | 0.64 | TACR1 (0.39) | HTR2CHTR2B | |
| SCHEMBL2365784 | 0.63 | HRH1 (0.66) | HTR2CHTR2BHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |