Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7480391 | 0.81 | PRCP (0.38) | PRCPKDM1AATMTDP1HTR2A | |
| SCHEMBL8900994 | 0.80 | ADRA2C (0.44) | GID4KDM1ATDP1 | |
| SCHEMBL6227686 | 0.80 | SLC18A3 (0.38) | PRCPCYP1A2CYP2D6CYP2C19HTR2B | |
| SCHEMBL472003 | 0.80 | SLC18A3 (0.38) | PRCPCYP1A2CYP2D6CYP2C19HTR2B | |
| SCHEMBL8531187 | 0.78 | ABCC9 (0.34) | — | |
| SCHEMBL14931991 | 0.77 | HTR2C (0.46) | MAPTKDM1ANPSR1CYP1A2CYP3A4 | |
| SCHEMBL8530413 | 0.77 | HTR2C (0.46) | MAPTKDM1ANPSR1CYP1A2CYP3A4 | |
| SCHEMBL8530406 | 0.76 | SLC6A2 (0.35) | — | |
| SCHEMBL8531757 | 0.73 | KDM1A (0.37) | KDM1AHTR2AHTR2CHTR2B | |
| SCHEMBL6002726 | 0.69 | MAOB (0.34) | MAPTACHEHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843966-A | Piperidine derivatives | GLAXO GROUP LIMITED (GB) | 1998-12-01 | — | — | US | disclosed |
| US-5703240-A | ANALGESICS; ANTIINFLAMMATORY AGENTS; NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS; GASTROINTESTINAL DISORDERS | GLAXO GROUP LIMITED (GB) | 1997-12-30 | — | — | US | disclosed |