Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC3 | Q13507 | 3/20 | 0.44 |
| ▸ | TRPC7 | Q9HCX4 | 3/20 | 0.44 |
| ▸ | CPT1A | P50416 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6004521 | 0.90 | TRPC3 (0.42) | TRPC3TRPC7CPT1ACTSKCTSB | |
| SCHEMBL4717811 | 0.87 | TRPC3 (0.51) | TRPC3TRPC7MMP13MMP1KDM4E | |
| SCHEMBL6004023 | 0.80 | CPT1A (0.45) | TRPC3TRPC7CPT1AMMP13MMP1 | |
| SCHEMBL4762496 | 0.74 | RAB9A (0.47) | MMP13MMP1KDM4ELMNATP53 | |
| SCHEMBL4721307 | 0.72 | TRPC3 (0.49) | TRPC3TRPC7MMP13MMP1KDM4E | |
| SCHEMBL6004395 | 0.71 | TSHR (0.43) | MMP13MMP1KDM4ELMNACTSK | |
| SCHEMBL29394187 | 0.71 | AADAT (0.53) | CPT1AKDM4ELMNATSHRL3MBTL1 | |
| SCHEMBL13209676 | 0.71 | AADAT (0.53) | CPT1AKDM4ELMNATSHRL3MBTL1 | |
| SCHEMBL13576750 | 0.71 | AADAT (0.53) | CPT1AKDM4ELMNATSHRL3MBTL1 | |
| SCHEMBL6003954 | 0.71 | MAPK14 (0.42) | CPT1AMMP13MMP1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060252807-A1 | Novel ortho-terphenyl inhibitors of p38 kinase and methods of treating inflammatory disorders | KALYPSYS, INC. | 2006-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252807-A1 | Novel ortho-terphenyl inhibitors of p38 kinase and methods of treating inflammatory disorders | MAPK1, MAP3K1, MAPK4 | TRPC3 1774/4885TRPC7 2577/4885CPT1A 4225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.