Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL719079 | 0.76 | IDO1 (0.50) | IDO1L3MBTL1TP53MAPTALDH1A1 | |
| SCHEMBL1306077 | 0.73 | MAPT (0.49) | IDO1L3MBTL1TP53MAPTALDH1A1 | |
| SCHEMBL492446 | 0.72 | PSMB8 (0.53) | IDO1L3MBTL1TP53MAPTALDH1A1 | |
| SCHEMBL5092877 | 0.72 | IDO1 (0.50) | IDO1L3MBTL1TP53MAPTALDH1A1 | |
| SCHEMBL15874315 | 0.72 | IDO1 (0.50) | IDO1L3MBTL1TP53MAPTALDH1A1 | |
| SCHEMBL3096380 | 0.72 | IDO1 (0.50) | IDO1L3MBTL1TP53MAPTALDH1A1 | |
| SCHEMBL30938811 | 0.72 | PSMB8 (0.53) | IDO1L3MBTL1TP53MAPTALDH1A1 | |
| SCHEMBL29800442 | 0.72 | IDO1 (0.50) | IDO1L3MBTL1TP53MAPTALDH1A1 | |
| SCHEMBL221981 | 0.72 | ALDH1A1 (0.51) | IDO1L3MBTL1MAPTALDH1A1RAB9A | |
| SCHEMBL719081 | 0.72 | MAPT (0.56) | IDO1L3MBTL1MAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |