Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.44 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | S100A9 | P06702 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002651 | 0.81 | KMO (0.46) | KMO | |
| SCHEMBL17626110 | 0.77 | AHR (0.46) | KMONOTUM | |
| SCHEMBL6001761 | 0.76 | NISCH (0.43) | NOTUM | |
| SCHEMBL5535439 | 0.75 | KMO (0.49) | KMOGRIN2BSLC1A5NOTUMGRM2 | |
| SCHEMBL6002864 | 0.73 | NOTUM (0.34) | NOTUM | |
| SCHEMBL6003160 | 0.72 | GPR3 (0.40) | — | |
| SCHEMBL5537301 | 0.72 | KMO (0.52) | KMOGRIN2BSLC1A5NOTUMGRM2 | |
| SCHEMBL14742275 | 0.71 | KMO (0.68) | KMOGRIN2B | |
| SCHEMBL5545853 | 0.71 | KMO (0.53) | KMOGRIN2BSLC1A5GRM2 | |
| SCHEMBL6002878 | 0.70 | MRGPRX4 (0.53) | KMOGRIN2BGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |