Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 7/20 | 0.54 |
| ▸ | KCNQ3 | O43525 | 6/20 | 0.54 |
| ▸ | KCNQ4 | P56696 | 3/20 | 0.54 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6004334 | 0.90 | RAB9A (0.51) | KCNQ2KCNQ3KCNQ4KCNQ5MAPK1 | |
| SCHEMBL6005439 | 0.88 | KCNQ2 (0.64) | KCNQ2KCNQ3KCNQ4KCNQ5MAPK1 | |
| SCHEMBL6004957 | 0.86 | KCNQ3 (0.55) | KCNQ2KCNQ3KCNQ4KCNQ5MAPK1 | |
| SCHEMBL6005471 | 0.84 | KCNQ3 (0.59) | KCNQ2KCNQ3KCNQ4KCNQ5MAPK1 | |
| SCHEMBL2235641 | 0.84 | KCNQ2 (0.70) | KCNQ2KCNQ3KCNQ4KCNQ5MAPK1 | |
| SCHEMBL30795264 | 0.84 | KCNQ2 (0.72) | KCNQ2KCNQ3KCNQ4KCNQ5MAPK1 | |
| SCHEMBL3102613 | 0.84 | KCNQ2 (0.72) | KCNQ2KCNQ3KCNQ4KCNQ5MAPK1 | |
| SCHEMBL6005020 | 0.82 | KCNQ3 (0.52) | KCNQ2KCNQ3KCNQ4KCNQ5MAPK1 | |
| SCHEMBL6004934 | 0.82 | MAPT (0.49) | KCNQ2KCNQ3KCNQ4KCNQ5MAPK1 | |
| SCHEMBL6004296 | 0.81 | MAPT (0.56) | KCNQ2KCNQ3MAPK1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060167087-A1 | Substituted aniline derivatives | H. LUNDBECK A/S (DK) | 2006-07-27 | — | — | US | disclosed |
| EP-1606247-A1 | SUBSTITUTED ANILINE DERIVATIVES | H. Lundbeck A/S (DK) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004080950-A1 | SUBSTITUTED ANILINE DERIVATIVES | H. LUNDBECK A/S (DK) | 2004-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167087-A1 | Substituted aniline derivatives | CYP3A43, UGT2B7, CYP3A7 | KCNQ2 2612/4885KCNQ3 2474/4885KCNQ4 3100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.