Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874989 | 0.75 | KDM1A (0.44) | KDM1AHTR1ALMNA | |
| Hydrochloric Acid SCHEMBL27303798 | 0.74 | KDM1A (0.42) | KDM1ASIGMAR1LMNA | |
| SCHEMBL28549626 | 0.72 | SIGMAR1 (0.41) | KDM1ASIGMAR1LMNA | |
| SCHEMBL28911543 | 0.72 | SIGMAR1 (0.41) | KDM1ASIGMAR1LMNA | |
| SCHEMBL28551246 | 0.72 | SIGMAR1 (0.41) | KDM1ASIGMAR1LMNA | |
| SCHEMBL3948798 | 0.71 | MAPK1 (0.37) | KDM1A | |
| SCHEMBL11750905 | 0.71 | SRD5A1 (0.40) | KDM1ACTSKHTR1ALMNATDP1 | |
| SCHEMBL7787278 | 0.70 | DRD3 (0.35) | KDM1A | |
| SCHEMBL27565839 | 0.69 | KDM1A (0.36) | KDM1AHTR1A | |
| SCHEMBL7782464 | 0.65 | ESR2 (0.48) | KDM1ASIGMAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |