Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | CHAT | P28329 | 5/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | SMPD2 | O60906 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002917 | 0.87 | RXRA (0.49) | RXRACHATHDAC8HDAC6MTNR1A | |
| SCHEMBL9819923 | 0.87 | RXRA (0.49) | RXRACHATHDAC8HDAC6MTNR1A | |
| SCHEMBL4626591 | 0.84 | RXRA (0.57) | RXRACHATHDAC8HDAC6MTNR1A | |
| SCHEMBL4626594 | 0.84 | RXRA (0.57) | RXRACHATHDAC8HDAC6MTNR1A | |
| SCHEMBL29399914 | 0.84 | RXRA (0.57) | RXRACHATHDAC8HDAC6MTNR1A | |
| SCHEMBL27525379 | 0.82 | RXRA (0.55) | RXRACHATHDAC8HDAC6MTNR1A | |
| SCHEMBL27493524 | 0.82 | RXRA (0.55) | RXRACHATHDAC8HDAC6MTNR1A | |
| SCHEMBL27495890 | 0.82 | RXRA (0.55) | RXRACHATHDAC8HDAC6MTNR1A | |
| SCHEMBL10741170 | 0.82 | CHAT (0.48) | RXRACHATHDAC8HDAC6MTNR1A | |
| SCHEMBL10741168 | 0.82 | CHAT (0.48) | RXRACHATHDAC8HDAC6MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |