SCHEMBL4626591

SCHEMBL4626591

C(/C=C/c1cccc2ccccc12)=C\c1cccc2ccccc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.57
CHAT P28329 5/20 0.53
HDAC8 Q9BY41 1/20 0.53
HDAC6 Q9UBN7 1/20 0.53
MTNR1A P48039 1/20 0.52
MTNR1B P49286 1/20 0.52
PTGS1 P23219 1/20 0.50
PTGS2 P35354 1/20 0.50
ALDH1A1 P00352 1/20 0.47
CYP1A1 P04798 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
MAPT P10636 1/20 0.47
HPGD P15428 1/20 0.47
NPY1R P25929 1/20 0.47
MAPK1 P28482 1/20 0.47
NPY2R P49146 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
CYP1B1 Q16678 1/20 0.47
KDM4E B2RXH2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4626594 1.00 RXRA (0.57) RXRACHATHDAC8HDAC6MTNR1A
SCHEMBL29399914 1.00 RXRA (0.57) RXRACHATHDAC8HDAC6MTNR1A
SCHEMBL27495890 0.98 RXRA (0.55) RXRACHATHDAC8HDAC6MTNR1A
SCHEMBL27493524 0.98 RXRA (0.55) RXRACHATHDAC8HDAC6MTNR1A
SCHEMBL27525379 0.98 RXRA (0.55) RXRACHATHDAC8HDAC6MTNR1A
SCHEMBL10706700 0.90 CHAT (0.62) RXRACHATHDAC8HDAC6MTNR1A
SCHEMBL10706694 0.90 CHAT (0.62) RXRACHATHDAC8HDAC6MTNR1A
SCHEMBL10706687 0.90 CHAT (0.62) RXRACHATHDAC8HDAC6MTNR1A
SCHEMBL10742158 0.89 RXRA (0.53) RXRACHATHDAC8HDAC6MTNR1A
SCHEMBL10742163 0.89 RXRA (0.53) RXRACHATHDAC8HDAC6MTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040132935-A1 Branched crystalline polypropylene EXXONMOBIL CHEMICAL PATENTS INC. 2004-07-08 US claimed
US-20040122191-A1 Supercritical polymerization process and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC 2004-06-24 US claimed
US-20040110910-A1 High temperature bulk polymerization of branched crystalline polypropylene EXXONMOBIL CHEMICAL PATENTS INC. 2004-06-10 US claimed
US-20040110909-A1 Branched diene-modified crystalline polypropylene terpolymers EXXONMOBIL CHEMICAL PATENTS, INC. 2004-06-10 US claimed
US-20040110911-A1 Diene-modified propylene copolymers EXXONMOBIL CHEMICAL PATENTS INC. 2004-06-10 US claimed
WO-2004037871-A1 BRANCHED CRYSTALLINE POLYPROPYLENE EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-05-06 WO claimed
EP-1119575-B1 BRIDGED METAL COMPLEXES DOW CHEMICAL CO (US) 2003-09-03 EP claimed
US-6500949-B2 ALPHA-OLEFIN POLYMERIZATION CATALYST DOW GLOBAL TECHNOLOGIES INC. 2002-12-31 US claimed
US-20010025115-A1 Bridged metal complexes DOW GLOBAL TECHNOLOGIES LLC 2001-09-27 US claimed
US-12503529-B2 Polymers of 4-substituted hexadiene and processes for production thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2025-12-23 US disclosed
US-12466902-B2 Non-coordinating anion type activators for use with polyolefin polymerization catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2025-11-11 US disclosed
EP-3941949-B1 METHODS FOR IMPROVING GAS PHASE POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC (US) 2025-10-22 EP disclosed
EP-3784648-B1 NON-COORDINATING ANION TYPE ACTIVATORS CONTAINING CATION HAVING BRANCHED ALKYL GROUPS EXXONMOBIL CHEMICAL PATENTS INC (US) 2025-07-02 EP disclosed
US-12202917-B2 Methods for improving gas phase polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2025-01-21 US disclosed
US-20010025115-A1 Bridged metal complexes DOW GLOBAL TECHNOLOGIES LLC 2001-09-27 US disclosed
US-6284905-B1 GROUP 4 TRANSITION METAL COMPLEX CONTAINING A BORON OR ALUMINUM BRIDGING GROUP CONTAINING A NITROGEN CONTAINING ELECTRON DONATING GROUP, ESPECIALLY AN AMIDO GROUP; OLEFIN SOLUTION OR SLURRY POLYMERIZATION CATALYSTS THE DOW CHEMICAL COMPANY 2001-09-04 US disclosed
EP-1119575-A1 BRIDGED METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 2001-08-01 EP disclosed
WO-2001046201-A1 GALLIUM OR INDIUM-BRIDGED GROUP 4 METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 2001-06-28 WO disclosed
WO-2000020462-A2 BRIDGED METAL COMPLEXES FOR GAS PHASE POLYMERIZATIONS BP CHEMICALS LIMITED (GB) 2000-04-13 WO disclosed
WO-2000020426-A1 BRIDGED METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 2000-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010025115-A1 Bridged metal complexes SLC39A14, NBAS, MCM4 RXRA 3522/4885CHAT 4688/4885HDAC8 1358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.