Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10659522 | 0.80 | HRH1 (0.40) | CAMK2AHRH1SLC6A4RIPK1SLC6A2 | |
| SCHEMBL19205830 | 0.80 | LTA4H (0.55) | HRH1SLC6A4RIPK1SLC6A2LTA4H | |
| SCHEMBL2046663 | 0.76 | HRH1 (0.60) | HRH1SLC6A4RIPK1SLC6A2LTA4H | |
| SCHEMBL27941087 | 0.76 | RHEB (0.42) | CAMK2AHRH1SLC6A4RIPK1SLC6A2 | |
| SCHEMBL10658806 | 0.75 | SLC6A4 (0.36) | CAMK2AHRH1SLC6A4RIPK1SLC6A2 | |
| SCHEMBL8942339 | 0.75 | TSHR (0.44) | LTA4HTSHRKMT2ALMNAGAA | |
| SCHEMBL2093110 | 0.74 | CAMK2A (0.49) | CAMK2AHRH1SLC6A4RIPK1SLC6A2 | |
| SCHEMBL23174980 | 0.73 | THRB (0.48) | CAMK2AKMT2AGAATTRSMN1; SMN2 | |
| SCHEMBL982234 | 0.71 | TTR (0.50) | LTA4HTSHRKMT2ATTRCTNNB1 | |
| SCHEMBL5034123 | 0.71 | LTA4H (0.44) | HRH1LTA4HTSHRKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |