Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6003073 | 0.86 | SIGMAR1 (0.39) | MAPT | |
| SCHEMBL4939867 | 0.72 | — | — | |
| SCHEMBL2090496 | 0.70 | SIGMAR1 (0.35) | MAPT | |
| SCHEMBL2095854 | 0.69 | SIGMAR1 (0.38) | MAPT | |
| SCHEMBL2093530 | 0.69 | SIGMAR1 (0.38) | MAPT | |
| SCHEMBL12050662 | 0.69 | — | — | |
| SCHEMBL4944247 | 0.67 | — | — | |
| SCHEMBL3965752 | 0.65 | FFAR1 (0.40) | — | |
| SCHEMBL4939885 | 0.63 | — | — | |
| SCHEMBL1678164 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |