SCHEMBL6003288

SCHEMBL6003288

CCCC12CC3CC(CC(N)(C3)C1)C2

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 10/20 0.71
GRIN3B O60391 10/20 0.71
GRIN1 Q05586 10/20 0.71
GRIN2A Q12879 10/20 0.71
GRIN2B Q13224 10/20 0.71
GRIN2C Q14957 10/20 0.71
GRIN3A Q8TCU5 10/20 0.71
POLB P06746 2/20 0.53
PKM P14618 1/20 0.44
LMNA P02545 2/20 0.41
SLC22A2 O15244 1/20 0.41
SLC22A1 O15245 1/20 0.41
TSHR P16473 1/20 0.41
NFKB1 P19838 1/20 0.41
STAT6 P42226 1/20 0.41
SLC47A1 Q96FL8 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
THRB P10828 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL657942 0.89 GRIN2D (0.67) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL658278 0.87 GRIN2D (0.65) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL657934 0.85 GRIN2D (0.62) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL21002581 0.85 GRIN2D (0.48) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL292537 0.83 GRIN2D (1.00) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Hydrochloric Acid SCHEMBL31431345 0.82 GRIN1 (0.96) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL25799584 0.82 GRIN1 (0.70) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Hydrochloric Acid SCHEMBL541940 0.82 GRIN1 (0.96) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL16269329 0.80 GRIN2D (0.60) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL16274382 0.80 GRIN2D (0.60) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116262698-B Novel 2- (1-hydroxypentyl) benzoic acid naphthenamine salt CHENGDU SHIBEIKANG BIOLOGICAL MEDICINE TECHNOLOGY Co.,Ltd. (CN) 2026-05-26 CN disclosed
EP-4685128-A1 NOVEL 2-(1-HYDROXYPENTYL) BENZOIC ACID CYCLOALKYL AMINE SALT Chengdu Shibeikang Biomedical Technology Co., Ltd. (CN) 2026-01-28 EP disclosed
WO-2024193721-A1 NOVEL 2-(1-HYDROXYPENTYL) BENZOIC ACID CYCLOALKYL AMINE SALT 成都施贝康生物医药科技有限公司 2024-09-26 WO disclosed
CN-116262698-A Novel 2- (1-hydroxypentyl) benzoic acid naphthenamine salt 成都施贝康生物医药科技有限公司 2023-06-16 CN disclosed
WO-2020232246-A1 COMPOSITIONS AND METHODS AGAINST STRESS-INDUCED AFFECTIVE DISORDERS AND THEIR ASSOCIATED SYMPTOMS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2020-11-19 WO disclosed
US-8481016-B2 Method for inhibition of potential-dependent cation channel KAO CORPORATION (JP) 2013-07-09 US disclosed
US-20130045177-A1 Method for Inhibition of Potential-Dependent Cation Channel KAO CORPORATION (JP) 2013-02-21 US disclosed
US-20060199816-A1 Aryl sulfonyl piperidines GILLESPIE PAUL 2006-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130045177-A1 Method for Inhibition of Potential-Dependent Cation Channel TRPM7, TRPM8, OR10J3 GRIN2D 399/4885GRIN3B 217/4885GRIN1 215/4885
US-20060199816-A1 Aryl sulfonyl piperidines GPR119, SLC5A2, GLS2 GRIN2D 2918/4885GRIN3B 4009/4885GRIN1 3356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.