SCHEMBL6003324

SCHEMBL6003324

Nc1cc(-c2ccccc2)c(-c2ccccc2)c(-c2ccccc2)c1N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.48
ALDH1A1 P00352 3/20 0.48
PDE4A P27815 1/20 0.42
PDE4B Q07343 1/20 0.42
PDE4C Q08493 1/20 0.42
PDE4D Q08499 1/20 0.42
PDE3B Q13370 1/20 0.42
PDE3A Q14432 1/20 0.42
SMARCA2 P51531 2/20 0.39
SMARCA4 P51532 2/20 0.39
PBRM1 Q86U86 2/20 0.39
BACE1 P56817 1/20 0.39
MAPT P10636 3/20 0.37
BRD4 O60885 1/20 0.37
NR1I2 O75469 1/20 0.37
MAOA P21397 2/20 0.37
LMNA P02545 3/20 0.36
HTT P42858 2/20 0.36
ALOX15 P16050 2/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29115742 0.87 HSD17B10 (0.48) HSD17B10ALDH1A1PDE4APDE4BPDE4C
SCHEMBL30697354 0.87 HSD17B10 (0.48) HSD17B10ALDH1A1PDE4APDE4BPDE4C
SCHEMBL21280056 0.84 HSD17B10 (0.50) HSD17B10ALDH1A1PDE4APDE4BPDE4C
SCHEMBL21278695 0.84 HSD17B10 (0.44) HSD17B10ALDH1A1PDE4APDE4BPDE4C
SCHEMBL530448 0.83 HSD17B10 (0.48) HSD17B10ALDH1A1PDE4APDE4BPDE4C
SCHEMBL29596767 0.83 HSD17B10 (0.48) HSD17B10ALDH1A1PDE4APDE4BPDE4C
SCHEMBL904510 0.83 HSD17B10 (0.48) HSD17B10ALDH1A1PDE4APDE4BPDE4C
Hydrochloric Acid SCHEMBL28480643 0.83 HSD17B10 (0.43) HSD17B10ALDH1A1PDE4APDE4BPDE4C
SCHEMBL27608247 0.82 ALDH1A1 (0.41) HSD17B10ALDH1A1MAPTBRD4MAOA
SCHEMBL27638258 0.82 ALDH1A1 (0.48) HSD17B10ALDH1A1PDE4APDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3162868-B1 THERMAL BASE GENERATOR, THERMOSETTING RESIN COMPOSITION, CURED FILM, CURED FILM MANUFACTURING METHOD, AND SEMICONDUCTOR DEVICE FUJIFILM CORP (JP) 2022-10-05 EP disclosed
CN-114437624-A Polyimide varnish, method for producing polyimide film, and method for producing patterned polyimide film 东京应化工业株式会社 2022-05-06 CN disclosed
WO-2021039782-A1 CURABLE RESIN COMPOSITION, CURED FILM, LAYERED PRODUCT, METHOD FOR PRODUCING CURED FILM, SEMICONDUCTOR DEVICE, RESIN, AND METHOD FOR PRODUCING RESIN 富士フイルム株式会社 2021-03-04 WO disclosed
US-7092608-B2 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2006-08-15 US disclosed
US-7082244-B2 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2006-07-25 US disclosed
US-20060159413-A1 POLYIMIDE OPTICAL MATERIALS, POLYIMIDE PRECURSOR SOLUTIONS AND OPTICAL WAVEGUIDE ELEMENTS KABUSHIKI KAISHA TOSHIBA (JP) 2006-07-20 US disclosed
US-20040197064-A1 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2004-10-07 US disclosed
EP-0610344-A1 POSITIVE PHOTORESISTS CONTAINING SOLUBILITY ENHANCERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-08-17 EP disclosed
EP-0601063-A1 FLUORINE-CONTAINING DIAMINES, POLYAMIDES, AND POLYIMIDES. DU PONT (US) 1994-06-15 EP disclosed
WO-1993009470-A1 POSITIVE PHOTORESISTS CONTAINING SOLUBILITY ENHANCERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-05-13 WO disclosed
EP-0062751-B1 OPTICAL DEVICE INCLUDING BIREFRINGENT POLYMER POLAROID CORPORATION (US) 1986-06-04 EP disclosed
US-4525413-A POLYAMIDES POLAROID CORPORATION (US) 1985-06-25 US disclosed
US-4521588-A Optical device including birefringent polyhydrazide polymer POLAROID CORPORATION (US) 1985-06-04 US disclosed
US-4520189-A OPTICAL FILTERS; CRYSTAL STRUCTURE POLAROID CORPORATION (US) 1985-05-28 US disclosed
US-4503248-A ANISOTROPIC POLYMERS POLAROID CORPORATION (US) 1985-03-05 US disclosed
EP-0061026-B1 SUBSTITUTED-QUATERPHENYLENE POLYAMIDES POLAROID CORPORATION (US) 1985-01-30 EP disclosed
US-4446305-A Optical device including birefringent polymer POLAROID CORPORATION (US) 1984-05-01 US disclosed
US-4393194-A OPTICAL FILTERS POLAROID CORPORATION (US) 1983-07-12 US disclosed
EP-0062751-A1 Optical device including birefringent polymer POLAROID CORPORATION (US) 1982-10-20 EP disclosed
EP-0061026-A1 Substituted-quaterphenylene polyamides POLAROID CORPORATION (US) 1982-09-29 EP disclosed