SCHEMBL904510

SCHEMBL904510

Nc1cc(-c2ccccc2)c(-c2ccccc2)c(N)c1-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.48
ALDH1A1 P00352 2/20 0.48
PDE4A P27815 1/20 0.42
PDE4B Q07343 1/20 0.42
PDE4C Q08493 1/20 0.42
PDE4D Q08499 1/20 0.42
PDE3B Q13370 1/20 0.42
PDE3A Q14432 1/20 0.42
SMARCA2 P51531 2/20 0.39
SMARCA4 P51532 2/20 0.39
PBRM1 Q86U86 2/20 0.39
BACE1 P56817 1/20 0.39
MAPT P10636 4/20 0.37
BRD4 O60885 1/20 0.37
NR1I2 O75469 1/20 0.37
MAOA P21397 1/20 0.37
LMNA P02545 3/20 0.36
KDM4E B2RXH2 2/20 0.36
MEN1 O00255 2/20 0.36
USP2 O75604 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29596767 1.00 HSD17B10 (0.48) HSD17B10ALDH1A1PDE4APDE4BPDE4C
SCHEMBL1901150 0.89 PDE4A (0.42) HSD17B10ALDH1A1PDE4APDE4BPDE4C
SCHEMBL22326302 0.86 ALDH1A1 (0.44) HSD17B10ALDH1A1MAPTBRD4MAOA
SCHEMBL21280056 0.84 HSD17B10 (0.50) HSD17B10ALDH1A1PDE4APDE4BPDE4C
SCHEMBL530448 0.83 HSD17B10 (0.48) HSD17B10ALDH1A1PDE4APDE4BPDE4C
SCHEMBL6003324 0.83 HSD17B10 (0.48) HSD17B10ALDH1A1PDE4APDE4BPDE4C
SCHEMBL6836070 0.82 ALDH1A1 (0.50) HSD17B10ALDH1A1PDE4APDE4BPDE4C
SCHEMBL21046679 0.80 HSD17B10 (0.44) HSD17B10ALDH1A1PDE4APDE4BPDE4C
SCHEMBL30594444 0.80 HSD17B10 (0.44) HSD17B10ALDH1A1PDE4APDE4BPDE4C
SCHEMBL25135347 0.78 HSD17B10 (0.48) HSD17B10ALDH1A1PDE4APDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4326731-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES Samsung Display Co., Ltd. (KR) 2024-02-28 EP disclosed
CN-117024286-A Organic compound and organic electroluminescent device comprising the same SK株式会社 2023-11-10 CN disclosed
US-11807656-B2 Polycyclic aromatic compound and light emission layer-forming composition KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-11-07 US disclosed
CN-116987108-A Polycyclic aromatic compound, material for organic element, composition for forming light-emitting layer, organic electroluminescent element, and device 学校法人关西学院 2023-11-03 CN disclosed
CN-113801151-B Condensed ring aromatic compound and application thereof 北京八亿时空液晶科技股份有限公司 2023-09-19 CN disclosed
US-11723263-B2 Organic electroluminescent element KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-08-08 US disclosed
CN-115947755-B Synthesis method of biaryl aniline axial chiral derivative 泽升科技(广州)有限公司 2023-05-09 CN disclosed
CN-116096201-A Delayed fluorescence organic electroluminescent element, display device and lighting device 学校法人关西学院 2023-05-09 CN disclosed
CN-115947755-A Synthetic method of biarylaniline axial chiral derivative 泽升科技(广州)有限公司 2023-04-11 CN disclosed
EP-4139315-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES Samsung Display Co., Ltd. (KR) 2023-03-01 EP disclosed
EP-3109253-B1 POLYCYCLIC AROMATIC COMPOUNDS AND THEIR USE AS ORGANIC DEVICE MATERIAL KWANSEI GAKUIN EDUCATIONAL FOUND (JP) 2018-10-24 EP disclosed
US-20180301629-A1 ORGANIC ELECTROLUMINESCENT ELEMENT KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2018-10-18 US disclosed
CN-108431984-A Delayed fluorescence organic electroluminescent element 学校法人关西学院 2018-08-21 CN disclosed
EP-3345911-A1 POLYCYCLIC AROMATIC COMPOUNDS AND THEIR USE AS ORGANIC DEVICE MATERIAL Kwansei Gakuin Educational Foundation (JP) 2018-07-11 EP disclosed
US-20180094000-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2018-04-05 US disclosed
CN-107851724-A Organic electric-field light-emitting element 学校法人关西学院 2018-03-27 CN disclosed
CN-107735879-A Polycyclc aromatic compound and luminescent layer formation composition 学校法人关西学院 2018-02-23 CN disclosed
CN-106905367-A Polycyclc aromatic compound, polymer and its manufacture method and its application 学校法人关西学院 2017-06-30 CN disclosed
EP-3109253-A1 POLYCYCLIC AROMATIC COMPOUND Kwansei Gakuin Educational Foundation (JP) 2016-12-28 EP disclosed
CN-105431439-A Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUND 2016-03-23 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11807656-B2 Polycyclic aromatic compound and light emission layer-forming composition ARNT, TYR, NLRP3 HSD17B10 4513/4885ALDH1A1 2119/4885PDE4A 4464/4885
US-20180094000-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION TYR, NOD2, AHR HSD17B10 4581/4885ALDH1A1 2965/4885PDE4A 4502/4885
US-11723263-B2 Organic electroluminescent element NR4A3, AFF4, NR4A1 HSD17B10 3755/4885ALDH1A1 2052/4885PDE4A 3986/4885
US-20180301629-A1 ORGANIC ELECTROLUMINESCENT ELEMENT LEF1, EPB41L2, EPB41 HSD17B10 3401/4885ALDH1A1 1008/4885PDE4A 4033/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.