Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5548079 | 0.81 | HSD11B1 (0.59) | HTR2CEPHX1HSD11B1CYP2D6MGLL | |
| Hydrochloric Acid SCHEMBL6208842 | 0.80 | MEN1 (0.59) | HTR2CEPHX1HSD11B1CYP2D6MGLL | |
| SCHEMBL11393976 | 0.75 | CYP2D6 (0.56) | HTR2CEPHX1HSD11B1CYP2D6MGLL | |
| SCHEMBL11393975 | 0.75 | CYP2D6 (0.56) | HTR2CEPHX1HSD11B1CYP2D6MGLL | |
| Tert-Butyl Formate SCHEMBL27968919 | 0.75 | HSD11B1 (0.49) | HTR2CEPHX1HSD11B1CYP2D6MGLL | |
| SCHEMBL4630575 | 0.73 | HTR2C (0.62) | HTR2CEPHX1HSD11B1EPHX2 | |
| SCHEMBL27852403 | 0.70 | EPHX1 (0.62) | HTR2CEPHX1EPHX2 | |
| Trifluoroacetic Acid SCHEMBL942293 | 0.70 | EPHX1 (0.52) | HTR2CEPHX1P2RY14EPHX2 | |
| SCHEMBL23390079 | 0.70 | HTR2C (0.68) | HTR2CEPHX1EPHX2 | |
| SCHEMBL17488206 | 0.70 | HTR2C (0.68) | HTR2CEPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |