Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.67 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002297 | 0.83 | CYP19A1 (0.72) | CYP19A1MAOAMAOB | |
| SCHEMBL2779577 | 0.80 | CYP19A1 (1.00) | CYP19A1 | |
| SCHEMBL11076987 | 0.80 | CYP19A1 (0.72) | CYP19A1MAOAMAOBKDM1A | |
| SCHEMBL11078445 | 0.80 | CYP19A1 (0.71) | CYP19A1 | |
| SCHEMBL4190208 | 0.77 | CYP19A1 (0.62) | CYP19A1 | |
| SCHEMBL4184614 | 0.74 | CYP19A1 (0.59) | CYP19A1 | |
| SCHEMBL4181298 | 0.74 | CYP19A1 (0.59) | CYP19A1 | |
| SCHEMBL4771129 | 0.73 | CYP19A1 (0.58) | CYP19A1KMT2A | |
| SCHEMBL10531992 | 0.73 | CYP19A1 (0.62) | CYP19A1 | |
| SCHEMBL10107833 | 0.71 | CYP19A1 (0.64) | CYP19A1MAOAMAOBKDM1ARCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060223875-A1 | Methods and compositions for production, formulation and use of 1-aryl-3-azabicyclo[3.1.0]hexanes | DOV PHARMACEUTICAL, INC. | 2006-10-05 | — | — | US | disclosed |
| US-20060058428-A1 | Fluorinated compounds having epoxy and vinyl ether functional groups | HONEYWELL INTERNATIONAL INC. | 2006-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223875-A1 | Methods and compositions for production, formulation and use of 1-aryl-3-azabicyclo[3.1.0]hexanes | HTR1B, SLC6A3, CYP1B1 | CYP19A1 461/4885MAOA 71/4885MAOB 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.