SCHEMBL6003499

SCHEMBL6003499

CC(=O)Nc1cccc(O)c1N

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
HPGD P15428 2/20 0.50
HDAC1 Q13547 3/20 0.48
POLB P06746 2/20 0.47
MAPT P10636 2/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
G6PD P11413 1/20 0.46
CASP7 P55210 1/20 0.46
CASP6 P55212 1/20 0.46
KDM4E B2RXH2 3/20 0.45
MAOA P21397 1/20 0.45
APOBEC3A P31941 1/20 0.45
GFER P55789 1/20 0.45
APOBEC3G Q9HC16 1/20 0.45
CYP2C19 P33261 1/20 0.44
GAA P10253 2/20 0.44
KMT2A Q03164 2/20 0.44
HSD17B10 Q99714 1/20 0.44
HDAC3 O15379 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5516360 0.82 ALDH1A1 (0.52) ALDH1A1HPGDHDAC1POLBMAPT
SCHEMBL19004112 0.80 ALDH1A1 (0.53) ALDH1A1HPGDHDAC1POLBMAPT
SCHEMBL29375572 0.79 GAA (0.63) ALDH1A1HPGDHDAC1POLBMAPT
SCHEMBL79487 0.79 GAA (0.63) ALDH1A1HPGDHDAC1POLBMAPT
SCHEMBL19181071 0.79 GAA (0.63) ALDH1A1HPGDHDAC1POLBMAPT
SCHEMBL20051714 0.79 HDAC1 (0.70) ALDH1A1HPGDHDAC1POLBNPC1
Hydrochloric Acid SCHEMBL28755176 0.79 ALDH1A1 (0.63) ALDH1A1HPGDHDAC1POLBNPC1
SCHEMBL249105 0.78 ALDH1A1 (0.52) ALDH1A1HPGDHDAC1POLBMAPT
SCHEMBL5725423 0.78 ALDH1A1 (0.57) ALDH1A1HPGDHDAC1POLBMAPT
SCHEMBL3585917 0.78 ALDH1A1 (0.47) ALDH1A1HPGDHDAC1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101204356-A Dye composition of acidic ph comprising 2,3-diamino-6,7-dihydro-1h,5h-pyrazolo[1,2-a]pyrazol-1-one, a coupler, a particular surfactant and an oxidizing agent OREAL (FR) 2008-06-25 CN disclosed
WO-2006087195-A2 DYE COMPOSITION COMPRISING AT LEAST ONE METHINE DYE OF PARTICULAR STRUCTURE AND PROCESS FOR IMPLEMENTATION THEREOF L'OREAL (FR) 2006-08-24 WO disclosed