Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.47 |
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | PPARD | Q03181 | 7/20 | 0.47 |
| ▸ | PPARA | Q07869 | 7/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TLR2 | O60603 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Myristic Acid SCHEMBL10384943 | 0.88 | CA1 (0.57) | EPHX2GPR84FABP3CA1 | |
| Decanoic Acid SCHEMBL28321982 | 0.88 | CA1 (0.57) | EPHX2GPR84FABP3CA1 | |
| Succinic Acid SCHEMBL29047529 | 0.87 | GPR84 (0.47) | EPHX2GPR84PPARGPPARDPPARA | |
| Bicarbonate SCHEMBL5377762 | 0.86 | EPHX2 (0.55) | EPHX2GPR84PPARGPPARDPPARA | |
| Bicarbonate SCHEMBL28494347 | 0.86 | EPHX2 (0.55) | EPHX2GPR84PPARGPPARDPPARA | |
| Acetic Acid SCHEMBL28201981 | 0.82 | EPHX2 (0.55) | EPHX2TSHRALDH1A1CA1 | |
| Acetic Acid SCHEMBL3645976 | 0.82 | EPHX2 (0.55) | EPHX2GPR84PPARGPPARDPPARA | |
| Acetic Acid SCHEMBL28730807 | 0.80 | EPHX2 (0.54) | EPHX2GPR84PPARGPPARDPPARA | |
| Acetic Acid SCHEMBL27751674 | 0.80 | EPHX2 (0.54) | EPHX2TSHRALDH1A1CA1 | |
| Succinic Acid SCHEMBL9193317 | 0.80 | CA1 (0.56) | GPR84FABP3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060036024-A1 | RELEASE COATING COMPOSITION FOR TAPE | NEOTEC CO. LIMITED (TW) | 2006-02-16 | — | — | US | claimed |
| US-20060036024-A1 | RELEASE COATING COMPOSITION FOR TAPE | NEOTEC CO. LIMITED (TW) | 2006-02-16 | — | — | US | disclosed |