Sugi Predict

Sugi Predict / Compounds / SCHEMBL6003716

SCHEMBL6003716

SCHEMBL6003716

Nc1ccc(Cc2ccc(N)cc2Br)c(Br)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.50
▸ TSHR P16473 3/20 0.50
▸ GAA P10253 2/20 0.50
▸ MAPK1 P28482 2/20 0.50
▸ HTT P42858 1/20 0.50
▸ ALDH1A1 P00352 7/20 0.41
▸ MEN1 O00255 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ ALOX15 P16050 2/20 0.39
▸ CYP3A4 P08684 4/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ HSD17B10 Q99714 2/20 0.36
▸ CYP1A2 P05177 1/20 0.36
▸ CASP7 P55210 1/20 0.36
▸ HIF1A Q16665 1/20 0.36
▸ CASP1 P29466 2/20 0.35
▸ RECQL P46063 1/20 0.35
▸ TAAR1 Q96RJ0 1/20 0.34
▸ SNCA P37840 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28798079 0.85 MAPT (0.40) MAPTTSHRGAAMAPK1HTT
SCHEMBL13284941 0.85 MAPT (0.40) MAPTTSHRGAAMAPK1HTT
SCHEMBL14267850 0.83 MAPT (0.39) MAPTTSHRGAAMAPK1HTT
SCHEMBL30599142 0.83 MAPT (0.41) MAPTTSHRGAAMAPK1HTT
SCHEMBL1684387 0.83 MAPT (0.41) MAPTTSHRGAAMAPK1HTT
SCHEMBL21191112 0.83 HTR2A (0.47) MAPTGAAKDM4ETDP1
SCHEMBL21915966 0.82 IDO1 (0.46) MAPTTSHRGAAMAPK1HTT
SCHEMBL15053856 0.80 MAPT (0.38) MAPTTSHRGAAMAPK1HTT
SCHEMBL11439517 0.80 TAAR1 (0.49) MAPTTSHRGAAMAPK1HTT
SCHEMBL2385465 0.78 CSNK2A1 (0.40) MAPTTSHRGAAMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2970342-B1 SUBSTITUTED SILAXANTHENIUM RED TO NEAR-INFRARED FLUOROCHROMES FOR IN VITRO AND IN VIVO IMAGING AND DETECTION VISEN MEDICAL INC (US) 2024-01-24 — — EP disclosed
US-20240001334-A1 ACTIVE HYDROGEN-CONTAINING ORGANIC COMPOUND SCAVENGER, COMPOSITION, AND APPLICATIONS THEREOF TOSOH CORPORATION (JP) 2024-01-04 — — US disclosed
EP-4257233-A1 ACTIVE HYDROGEN-CONTAINING ORGANIC COMPOUND SCAVENGER, COMPOSITION, AND APPLICATIONS THEREOF Tosoh Corporation (JP) 2023-10-11 — — EP disclosed
CN-116437970-A Active hydrogen-containing organic compound capturing agents, compositions and uses thereof 东曹株式会社 2023-07-14 — — CN disclosed
CN-110662795-B Prepreg, method for producing same, laminate, printed wiring board, and semiconductor package 昭和电工材料株式会社 2022-12-06 — — CN disclosed
CN-110678505-B Method for producing prepreg, laminated board, printed wiring board, and semiconductor package 昭和电工材料株式会社 2022-08-23 — — CN disclosed
CN-110678505-A Method for producing prepreg, laminate, printed wiring board, and semiconductor package 日立化成株式会社 2020-01-10 — — CN disclosed
CN-110662795-A Prepreg, method for producing same, laminate, printed wiring board, and semiconductor package 日立化成株式会社 2020-01-07 — — CN disclosed
US-9649389-B2 Substituted silaxanthenium red to near-infrared fluorochromes for in vitro and in vivo imaging and detection VISEN MEDICAL, INC. (US) 2017-05-16 — — US disclosed
EP-2970342-A1 SUBSTITUTED SILAXANTHENIUM RED TO NEAR-INFRARED FLUOROCHROMES FOR IN VITRO AND IN VIVO IMAGING AND DETECTION VisEn Medical, Inc. (US) 2016-01-20 — — EP disclosed
US-20140314677-A1 SUBSTITUTED SILAXANTHENIUM RED TO NEAR-INFRARED FLUOROCHROMES FOR IN VITRO AND IN VIVO IMAGING AND DETECTION VISEN MEDICAL, INC. (US) 2014-10-23 — — US disclosed
WO-2014144793-A1 SUBSTITUTED SILAXANTHENIUM RED TO NEAR-INFRARED FLUOROCHROMES FOR IN VITRO AND IN VIVO IMAGING AND DETECTION VISEN MEDICAL, INC. (US) 2014-09-18 — — WO disclosed
US-8822118-B2 Toner, development agent, and image forming apparatus RICOH COMPANY, LTD. (JP) 2014-09-02 — — US disclosed
US-20060251379-A1 Optical element, process for producing optical element, coating equipment, and coating method KURODA TOSHIHIRO 2006-11-09 — — US disclosed
EP-0336391-B1 Reversibly color-changeable materials TEIJIN LTD (JP) 1994-01-26 — — EP disclosed
US-5068062-A Crosslinked resin containing 4,4*-diaminodiphenylmethane units with the amine quaternized and an electrolytic material TEIJIN LIMITED (JP) 1991-11-26 — — US disclosed
EP-0405329-A1 Adhesive stick having improved adhesive band strength Henkel Kommanditgesellschaft auf Aktien (DE) 1991-01-02 — — EP disclosed
EP-0336391-A2 Reversibly color-changeable materials TEIJIN LIMITED (JP) 1989-10-11 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140314677-A1 SUBSTITUTED SILAXANTHENIUM RED TO NEAR-INFRARED FLUOROCHROMES FOR IN VITRO AND IN VIVO IMAGING AND DETECTION IK, MKI67, SNRPE MAPT 450/4885TSHR 4657/4885GAA 2202/4885
US-20240001334-A1 ACTIVE HYDROGEN-CONTAINING ORGANIC COMPOUND SCAVENGER, COMPOSITION, AND APPLICATIONS THEREOF CBR1, ADH1C, ADH1A MAPT 4419/4885TSHR 3113/4885GAA 4158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.