SCHEMBL6004170

SCHEMBL6004170

O=C(O)c1cccc(CCCc2ccccc2CCCc2cccc(C(=O)O)c2C(=O)O)c1C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 4/20 0.57
BID P55957 4/20 0.53
MCL1 Q07820 4/20 0.53
BCL2L1 Q07817 3/20 0.53
BAK1 Q16611 3/20 0.53
PPARA Q07869 3/20 0.49
KAT8 Q9H7Z6 2/20 0.49
PPARG P37231 2/20 0.49
EP300 Q09472 1/20 0.49
KAT2A Q92830 1/20 0.49
KAT2B Q92831 1/20 0.49
KAT5 Q92993 1/20 0.49
SAE1 Q9UBE0 1/20 0.49
ALDH1A1 P00352 1/20 0.46
ALOX15 P16050 1/20 0.46
HMGB1 P09429 1/20 0.46
SLC16A3 O15427 2/20 0.46
CLCN2 P51788 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5114102 0.96 FOLH1 (0.56) FOLH1BIDMCL1BCL2L1BAK1
SCHEMBL10885451 0.92 BID (0.56) FOLH1BIDMCL1BCL2L1BAK1
SCHEMBL18038407 0.91 BID (0.65) FOLH1BIDMCL1BCL2L1BAK1
SCHEMBL9330418 0.91 BID (0.58) FOLH1BIDMCL1BCL2L1BAK1
SCHEMBL211983 0.91 BID (0.58) FOLH1BIDMCL1BCL2L1BAK1
SCHEMBL22912 0.88 FOLH1 (0.59) FOLH1BIDMCL1BCL2L1BAK1
SCHEMBL5695801 0.87 FOLH1 (0.51) FOLH1BIDMCL1BCL2L1BAK1
SCHEMBL247983 0.86 BID (0.72) FOLH1BIDMCL1BCL2L1BAK1
SCHEMBL2853619 0.86 BID (0.72) FOLH1BIDMCL1BCL2L1BAK1
Benzene SCHEMBL9187610 0.86 BID (0.62) FOLH1BIDMCL1BCL2L1BAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7092608-B2 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2006-08-15 US disclosed
US-7082244-B2 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2006-07-25 US disclosed
US-20060159413-A1 POLYIMIDE OPTICAL MATERIALS, POLYIMIDE PRECURSOR SOLUTIONS AND OPTICAL WAVEGUIDE ELEMENTS KABUSHIKI KAISHA TOSHIBA (JP) 2006-07-20 US disclosed
US-20040197064-A1 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2004-10-07 US disclosed