SCHEMBL6004557

SCHEMBL6004557

C=CCc1ccc(N)cc1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.50
GABRB2 P47870 4/20 0.50
POLB P06746 2/20 0.43
PRKCI P41743 1/20 0.43
XDH P47989 1/20 0.42
TSHR P16473 1/20 0.42
CASP1 P29466 1/20 0.42
ACHE P22303 3/20 0.42
SRD5A1 P18405 1/20 0.41
GAA P10253 3/20 0.41
MAPT P10636 3/20 0.41
ALDH1A1 P00352 3/20 0.41
MEN1 O00255 2/20 0.41
CNR1 P21554 2/20 0.41
CNR2 P34972 2/20 0.41
KMT2A Q03164 2/20 0.41
AKR1B1 P15121 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH2 P05091 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3819967 0.86 GABRA1 (0.68) GABRA1GABRB2POLBPRKCIXDH
Hydrochloric Acid SCHEMBL11795018 0.84 GABRA1 (0.66) GABRA1GABRB2POLBPRKCIXDH
SCHEMBL5548473 0.83 GABRA1 (0.42) GABRA1GABRB2POLBPRKCIXDH
SCHEMBL1772134 0.81 GABRA1 (0.41) GABRA1GABRB2POLBPRKCIXDH
Ethylene SCHEMBL27977906 0.81 GABRA1 (0.41) GABRA1GABRB2POLBPRKCIXDH
SCHEMBL2234679 0.80 PRKCI (0.43) POLBPRKCITSHRCASP1ACHE
SCHEMBL69697 0.79 TYR (0.58) GABRA1GABRB2POLBXDHTSHR
SCHEMBL8761713 0.79 TSHR (0.48) POLBPRKCITSHRCASP1ACHE
2-Allylphenol SCHEMBL10409346 0.78 GABRA1 (0.48) GABRA1GABRB2POLBPRKCITSHR
SCHEMBL10445566 0.78 PRKCI (0.50) GABRA1GABRB2POLBPRKCITSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7018426-B2 Oxidation dye WELLA AG (DE) 2006-03-28 US disclosed
US-20030159222-A1 Oxidation dye HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2003-08-28 US disclosed
US-5409503-A High color intensity red shades WELLA AKTIENGESELLSCHAFT (DE) 1995-04-25 US disclosed
US-4094635-A Meta-aminophenol sulfonamides as couplers in hair dye compositions L'OREAL (FR) 1978-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030159222-A1 Oxidation dye KRT18, NOX4, VIM GABRA1 4622/4885GABRB2 4350/4885POLB 462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.