Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 15/20 | 0.59 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6004049 | 0.85 | TGM2 (0.64) | TGM2CYP1A2 | |
| SCHEMBL6002856 | 0.84 | TGM2 (0.57) | TGM2 | |
| SCHEMBL4929227 | 0.84 | TGM2 (0.82) | TGM2CTSLCTSBCTSS | |
| SCHEMBL4929220 | 0.84 | TGM2 (0.82) | TGM2CTSLCTSBCTSS | |
| SCHEMBL6004042 | 0.84 | TGM2 (0.82) | TGM2CTSLCTSBCTSS | |
| SCHEMBL6002875 | 0.84 | TGM2 (0.59) | TGM2CYP1A2 | |
| SCHEMBL6002850 | 0.83 | TGM2 (0.59) | TGM2CYP1A2 | |
| SCHEMBL4395083 | 0.74 | TGM2 (1.00) | TGM2CTSLCTSBCTSS | |
| SCHEMBL4302758 | 0.74 | TGM2 (1.00) | TGM2CTSLCTSBCTSS | |
| SCHEMBL13934064 | 0.74 | TGM2 (1.00) | TGM2CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706129-A1 | DRUG THERAPY FOR CELIAC SPRUE | The Board of Trustees of The Leland Stanford Junior University (US) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005049064-A1 | DRUG THERAPY FOR CELIAC SPRUE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2005-06-02 | — | — | WO | disclosed |