Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 13/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.41 |
| ▸ | ITGAV | P06756 | 5/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002850 | 0.94 | TGM2 (0.59) | TGM2CYP1A2ITGB3ITGAV | |
| SCHEMBL6002875 | 0.87 | TGM2 (0.59) | TGM2CYP1A2ITGB3ITGA2B | |
| SCHEMBL9825352 | 0.86 | TGM2 (0.68) | TGM2CYP1A2 | |
| SCHEMBL6002856 | 0.86 | TGM2 (0.57) | TGM2 | |
| SCHEMBL1367897 | 0.85 | TGM2 (0.63) | TGM2CYP1A2ITGB3ITGAV | |
| SCHEMBL6004588 | 0.85 | TGM2 (0.59) | TGM2CYP1A2 | |
| SCHEMBL1091900 | 0.82 | TGM2 (0.72) | TGM2CYP1A2 | |
| SCHEMBL1103747 | 0.82 | TGM2 (0.72) | TGM2CYP1A2 | |
| SCHEMBL1091898 | 0.82 | TGM2 (0.72) | TGM2CYP1A2 | |
| SCHEMBL4598758 | 0.81 | TGM2 (0.62) | TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706129-A1 | DRUG THERAPY FOR CELIAC SPRUE | The Board of Trustees of The Leland Stanford Junior University (US) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005049064-A1 | DRUG THERAPY FOR CELIAC SPRUE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2005-06-02 | — | — | WO | disclosed |